N- 烷基苯胺的电化学硒环化反应：获得 3-硒基喹啉类化合物

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2024-09-12 DOI:10.1016/j.tet.2024.134257

Longqiang Zhao, Huimin Li, Mengyu Peng, Shoucai Wang, Mingzhe Li, Qingge Zhao, Wenxiu Huang, Guangbin Jiang, Fanghua Ji

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引用次数: 0

摘要

3 -硒基喹啉类化合物是一类重要的化合物，在医药和合成化学中有着重要的应用。在此，我们介绍了一种在非分裂电解条件下的电化学氧化硒环化方法，从而为获得 3-硒基喹啉类化合物提供了一种有效的途径。该方法绿色环保，无外部氧化剂，反应时间短，底物范围广，易于放大到克级，这些优点充分证明了该方法的优越性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Electrochemical selenocyclization of N-alkyl anilines: Access to 3-selenyl quinolines

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Electrochemical selenocyclization of N-alkyl anilines: Access to 3-selenyl quinolines

3-Selenyl quinolines are an important class of compounds that have found significant applications in pharmaceuticals and synthetic chemistry. Herein, we describe an electrochemical oxidative selenocyclization under undivided electrolytic conditions, thereby providing an efficient rout to access 3-selenyl quinolines. The merit of this method has been well demonstrated by its green and environmental-friendly conditions, being external oxidant-free, short reaction time, broad substrate scope and ease of scale-up to gram scale.

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.