用甲基化敏感型高分辨熔融法（MS-HRM）测定人血浆中的无细胞DNA（cfDNA）甲基化情况以诊断妊娠期糖尿病（GDM）

IF 1.6 4区化学 Q3 CHEMISTRY, ANALYTICAL

Analytical Letters Pub Date : 2024-09-02 DOI:10.1080/00032719.2024.2399182

Zhiyu Liu, Yuwei Yang, Yunfei Bai, Qinyu Ge

引用次数: 0

摘要

人们对用于无创产前诊断的无细胞 DNA（cfDNA）甲基化非常感兴趣。我们采用简单的方法研究了母体血浆 DNA 甲基化。80份血浆样本...

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Determination of Cell-Free DNA (cfDNA) Methylation by Methylation-Sensitive High-Resolution Melting (MS-HRM) in Human Plasma for the Diagnosis of Gestational Diabetes Mellitus (GDM)

Considerable interest has focused on cell-free DNA (cfDNA) methylation for noninvasive prenatal diagnosis. We investigated maternal plasma DNA methylation using a simple protocol. Eighty plasma sam...

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来源期刊

Analytical Letters 化学-分析化学

CiteScore

4.10

自引率

5.00%

发文量

218

审稿时长

2.1 months

期刊介绍： Analytical Letters is an international medium for the rapid publication of original research papers, accelerated articles, or mini-reviews on important developments in all areas of analytical chemistry, including electrochemistry, mass spectrometry, separations, and spectroscopy. Papers are welcomed that consider fundamental developments, new or improved instrumentation and sensors, and applications of analytical chemistry in all areas that include biological and clinical science, engineering and instrumentation science, environmental chemistry and analysis, geochemistry, materials science, nanotechnology, and physics.