犬肾上腺肿瘤腹腔镜乙醇消融术获得成功

IF 1.8 3区农林科学 Q2 VETERINARY SCIENCES

Veterinary Medicine and Science Pub Date : 2024-09-17 DOI:10.1002/vms3.70020

Shimon Furusato, Eriko Kondo, Yu Tamura, Yu Tsuyama

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引用次数: 0

摘要

肾上腺切除术是治疗犬肾上腺肿瘤的金标准，但由于患者年龄、基础疾病和围手术期死亡率等原因，并不总是推荐采用这种方法。在人类医学中，乙醇消融术是一种适用于手术条件较差的候选者的替代方法。一只 13 岁的绝育雌性玩具贵宾犬患有皮质醇增多症，并伴有严重血尿。超声波检查发现左肾上腺和右肾肿瘤。由于手术风险较高，患者同时接受了开腹右肾切除术和左肾上腺肿瘤乙醇消融术。乙醇注射后出现的并发症包括一过性高血压和心律失常，但均自行缓解。肾上腺肿瘤在 2.5 个月内缩小，皮质醇水平在 8 天内恢复正常，并在 12 个月内保持稳定。在没有使用曲洛司坦的情况下，没有观察到皮质醇过高的症状，直到因肾功能不全死亡。尸检显示，消融的左肾上腺是肾上腺皮质肿瘤，已经缩小。对于高风险犬类患者来说，乙醇消融可能是肾上腺切除术的可行替代方案。

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Successful laparotomic ethanol ablation for an adrenal tumour in a dog

Adrenalectomy is the gold standard for canine adrenal tumours, but not always recommended due to patient age, underlying conditions and perioperative mortality. Ethanol ablation is an alternative in human medicine for poor surgical candidates. A 13‐year‐old neutered female toy‐poodle with hypercortisolism presented with severe haematuria. Ultrasonography revealed left adrenal and right kidney tumours. Due to high surgical risk, simultaneous laparotomic right nephroureterectomy and ethanol ablation of the left adrenal tumour were performed. Post‐ethanol injection complications included transient hypertension and arrhythmia, which resolved spontaneously. The adrenal tumour size decreased within 2.5 months, and cortisol levels normalised within 8 days, remaining stable for 12 months. No hypercortisolism signs were observed without trilostane until death from renal insufficiency. Autopsy showed that the ablated left adrenal gland was an adrenocortical tumour and had shrunk. Ethanol ablation may be a feasible alternative to adrenalectomy for high‐risk canine patients.

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来源期刊

Veterinary Medicine and Science Veterinary-General Veterinary

CiteScore

3.00

自引率

0.00%

发文量

296

期刊介绍： Veterinary Medicine and Science is the peer-reviewed journal for rapid dissemination of research in all areas of veterinary medicine and science. The journal aims to serve the research community by providing a vehicle for authors wishing to publish interesting and high quality work in both fundamental and clinical veterinary medicine and science. Veterinary Medicine and Science publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper. We aim to be a truly global forum for high-quality research in veterinary medicine and science, and believe that the best research should be published and made widely accessible as quickly as possible. Veterinary Medicine and Science publishes papers submitted directly to the journal and those referred from a select group of prestigious journals published by Wiley-Blackwell. Veterinary Medicine and Science is a Wiley Open Access journal, one of a new series of peer-reviewed titles publishing quality research with speed and efficiency. For further information visit the Wiley Open Access website.