男性乳腺癌转移至肝脏:病例报告。

IF 2.5 4区 医学 Q3 ONCOLOGY
Mingming Jiang,Linyun Li,Hongjie Liu,Hua Xie
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引用次数: 0

摘要

乳腺癌(BC)仍然是影响女性患者的最常见恶性疾病之一,它几乎可以转移到身体的每一个部位。乳腺癌很少发生在男性身上,因此男性很少发生乳腺癌肝转移(BCLM)。然而,本研究报告了一名 55 岁的男性患者,他在 5 年前接受了 BC 手术。治疗后,患者定期接受积极随访。最近,患者因胸闷接受检查,发现肝脏占位性病变。患者的上腹部增强计算机断层扫描图像显示,肝脏密度不均匀,肝脏有肿块。在超声波的引导下,采用粗针活检对肝脏肿瘤进行了检查。病理结果显示,患者的 E-粘连蛋白、雌激素受体、孕酮受体、人表皮生长因子受体 2、GATA 结合蛋白 3 和 CK7 均呈阳性。患者随后被诊断为 BCLM。患者接受了盐酸多柔比星、环磷酰胺和多西他赛治疗,并定期随访。本病例报告强调,BCLM 不仅见于女性,也见于越来越多的男性,男性 BC 患者也可能发生肝转移。BCLM是一个复杂的过程,因此希望本病例报告能增进人们对男性BCLM及其发病机制的了解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Male breast cancer metastasising to the liver: A case report.
Breast cancer (BC) remains one of the most common malignant diseases affecting female patients, and it can metastasize to nearly every part of the body. BC is rare in men, and therefore men rarely develop BC liver metastases (BCLMs). However, the present study reports a 55-year-old male patient who underwent surgery 5 years ago for BC. After treatment, the patient was actively followed up regularly. Recently, the patient was examined for chest tightness, and liver space-occupying lesions were found. The upper abdominal enhanced computed tomography images of the patient showed that the liver density was not uniform and that the liver had a mass. A crude needle biopsy was used to examine the liver tumour under the guidance of ultrasound. The pathology revealed that the patient was positive for E-cadherin, oestrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, GATA binding protein 3 and CK7. The patient was subsequently diagnosed with BCLM. The patient was treated with doxorubicin hydrochloride, cyclophosphamide, Docetaxel and followed up regularly. The present case report emphasizes that BC is found not only in women but also in an increasing number of men, and that liver metastasis can occur in males with BC. BCLM is a complex process, and therefore it is hoped this case report will improve the understanding of male BCLM and the mechanism of this disease.
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来源期刊
Oncology Letters
Oncology Letters ONCOLOGY-
CiteScore
5.70
自引率
0.00%
发文量
412
审稿时长
2.0 months
期刊介绍: Oncology Letters is a monthly, peer-reviewed journal, available in print and online, that focuses on all aspects of clinical oncology, as well as in vitro and in vivo experimental model systems relevant to the mechanisms of disease. The principal aim of Oncology Letters is to provide the prompt publication of original studies of high quality that pertain to clinical oncology, chemotherapy, oncogenes, carcinogenesis, metastasis, epidemiology and viral oncology in the form of original research, reviews and case reports.
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