从日本黑牛身上分离出新型牛帕雷奇病毒并确定其遗传特征

IF 2.5 4区医学 Q3 VIROLOGY

Archives of Virology Pub Date : 2024-09-16 DOI:10.1007/s00705-024-06120-5

Mami Oba, Mayo Shimotori, Natsuko Teshima, Lisa Yamaguchi, Hitoshi Takemae, Shoichi Sakaguchi, Hiroho Ishida, Hironobu Murakami, Tetsuya Mizutani, Makoto Nagai

{"title":"从日本黑牛身上分离出新型牛帕雷奇病毒并确定其遗传特征","authors":"Mami Oba, Mayo Shimotori, Natsuko Teshima, Lisa Yamaguchi, Hitoshi Takemae, Shoichi Sakaguchi, Hiroho Ishida, Hironobu Murakami, Tetsuya Mizutani, Makoto Nagai","doi":"10.1007/s00705-024-06120-5","DOIUrl":null,"url":null,"abstract":"<div><p>Novel bovine parechoviruses (Bo ParVs) were isolated from the feces of Japanese black cattle. Phylogenetic analysis revealed that the novel Bo ParVs formed an independent cluster, exhibiting 72.2–75.6% nucleotide sequence identity to previous Bo ParVs, suggesting that they represent a new genotype. Bo ParVs, including the novel Bo ParVs, shared sequence similarity with each other in the 3' untranslated region (3'UTR) and exhibited low sequence similarity (<38.9% identity) to other parechoviruses. However, a secondary structure prediction of the 3'UTR revealed that the Bo ParVs shared conserved motifs in domain 2 with parechovirus B and E, suggesting some evolutionary constrains in this region.</p></div>","PeriodicalId":8359,"journal":{"name":"Archives of Virology","volume":"169 10","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00705-024-06120-5.pdf","citationCount":"0","resultStr":"{\"title\":\"Isolation and genetic characterization of novel bovine parechoviruses from Japanese black cattle\",\"authors\":\"Mami Oba, Mayo Shimotori, Natsuko Teshima, Lisa Yamaguchi, Hitoshi Takemae, Shoichi Sakaguchi, Hiroho Ishida, Hironobu Murakami, Tetsuya Mizutani, Makoto Nagai\",\"doi\":\"10.1007/s00705-024-06120-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Novel bovine parechoviruses (Bo ParVs) were isolated from the feces of Japanese black cattle. Phylogenetic analysis revealed that the novel Bo ParVs formed an independent cluster, exhibiting 72.2–75.6% nucleotide sequence identity to previous Bo ParVs, suggesting that they represent a new genotype. Bo ParVs, including the novel Bo ParVs, shared sequence similarity with each other in the 3' untranslated region (3'UTR) and exhibited low sequence similarity (<38.9% identity) to other parechoviruses. However, a secondary structure prediction of the 3'UTR revealed that the Bo ParVs shared conserved motifs in domain 2 with parechovirus B and E, suggesting some evolutionary constrains in this region.</p></div>\",\"PeriodicalId\":8359,\"journal\":{\"name\":\"Archives of Virology\",\"volume\":\"169 10\",\"pages\":\"\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://link.springer.com/content/pdf/10.1007/s00705-024-06120-5.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Virology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00705-024-06120-5\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VIROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Virology","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00705-024-06120-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VIROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

从日本黑牛的粪便中分离出了新型牛帕氏病毒（Bo ParVs）。系统进化分析表明，新型Bo ParVs形成了一个独立的群，与以前的Bo ParVs相比，核苷酸序列同一性为72.2-75.6%，表明它们代表了一种新的基因型。包括新型 Bo ParVs 在内的 Bo ParVs 在 3' 非翻译区（3'UTR）中的序列彼此相似，与其他帕雷奇病毒的序列相似性较低（38.9%）。然而，3'UTR的二级结构预测显示，Bo ParVs与帕雷奇病毒B和E在第2结构域共享保守基团，这表明该区域存在一些进化限制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Isolation and genetic characterization of novel bovine parechoviruses from Japanese black cattle

查看原文本刊更多论文

Isolation and genetic characterization of novel bovine parechoviruses from Japanese black cattle

Novel bovine parechoviruses (Bo ParVs) were isolated from the feces of Japanese black cattle. Phylogenetic analysis revealed that the novel Bo ParVs formed an independent cluster, exhibiting 72.2–75.6% nucleotide sequence identity to previous Bo ParVs, suggesting that they represent a new genotype. Bo ParVs, including the novel Bo ParVs, shared sequence similarity with each other in the 3' untranslated region (3'UTR) and exhibited low sequence similarity (<38.9% identity) to other parechoviruses. However, a secondary structure prediction of the 3'UTR revealed that the Bo ParVs shared conserved motifs in domain 2 with parechovirus B and E, suggesting some evolutionary constrains in this region.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Archives of Virology 医学-病毒学

CiteScore

5.10

自引率

7.40%

发文量

324

审稿时长

4.5 months

期刊介绍： Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.