COVID-19 和其他病毒性疾病中的自身抗体：分子、细胞和临床视角

IF 9 2区医学 Q1 VIROLOGY

Reviews in Medical Virology Pub Date : 2024-09-18 DOI:10.1002/rmv.2583

Srijan Chatterjee, Manojit Bhattacharya, Sanskriti Saxena, Sang‐Soo Lee, Chiranjib Chakraborty

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引用次数: 0

摘要

自身抗体是免疫系统产生的抗体，会错误地攻击人体细胞和组织。COVID-19 大流行使得自身抗体与病原体感染的严重程度以及感染痊愈后多种自身免疫性疾病的出现联系起来。本综述文章概述了自身免疫性疾病以及自身抗体在 COVID-19 和其他传染病中的功能。我们还研究了在 COVID-19 和其他感染性疾病中发现的不同类别的自身抗体，包括它们导致疾病严重程度的潜在途径。此外，文章还强调了疫苗诱导的自身抗体与不良后果之间可能存在的联系。综述还讨论了自身抗体的治疗前景。本文通过全面评估最新研究成果，增进了我们对自身抗体与 COVID-19 之间错综复杂的相互作用的了解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Autoantibodies in COVID‐19 and Other Viral Diseases: Molecular, Cellular, and Clinical Perspectives

Autoantibodies are immune system‐produced antibodies that wrongly target the body's cells and tissues for attack. The COVID‐19 pandemic has made it possible to link autoantibodies to both the severity of pathogenic infection and the emergence of several autoimmune diseases after recovery from the infection. An overview of autoimmune disorders and the function of autoantibodies in COVID‐19 and other infectious diseases are discussed in this review article. We also investigated the different categories of autoantibodies found in COVID‐19 and other infectious diseases including the potential pathways by which they contribute to the severity of the illness. Additionally, it also highlights the probable connection between vaccine‐induced autoantibodies and their adverse outcomes. The review also discusses the therapeutic perspectives of autoantibodies. This paper advances our knowledge about the intricate interaction between autoantibodies and COVID‐19 by thoroughly assessing the most recent findings.

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来源期刊

Reviews in Medical Virology 医学-病毒学

CiteScore

21.40

自引率

0.90%

发文量

期刊介绍： Reviews in Medical Virology aims to provide articles reviewing conceptual or technological advances in diverse areas of virology. The journal covers topics such as molecular biology, cell biology, replication, pathogenesis, immunology, immunization, epidemiology, diagnosis, treatment of viruses of medical importance, and COVID-19 research. The journal has an Impact Factor of 6.989 for the year 2020. The readership of the journal includes clinicians, virologists, medical microbiologists, molecular biologists, infectious disease specialists, and immunologists. Reviews in Medical Virology is indexed and abstracted in databases such as CABI, Abstracts in Anthropology, ProQuest, Embase, MEDLINE/PubMed, ProQuest Central K-494, SCOPUS, and Web of Science et,al.