准分子激光冠状动脉血管成形术:临床疗效微型综述

Gbolahan Olatunji, Emmanuel Kokori, John Aboje, Saad Mohammed, Olamide Asifat, David Timilehin Isarinade, Ismaila Ajayi Yusuf, David B. Olawade, Nicholas Aderinto
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引用次数: 0

摘要

准分子激光冠状动脉成形术(ELCA)已发展成为经皮冠状动脉介入治疗(PCI)的关键要素,对手术的疗效和安全性产生了重大影响。这篇微型综述探讨了 ELCA 的应用,重点是其疗效和临床结果。通过对主要数据库的检索,确定了自 ELCA 诞生以来的相关研究。纳入标准包括在冠状动脉干预中探索 ELCA 的各种研究设计,并通过严格的数据提取确保其准确性和完整性。叙述性综述介绍了各项研究的主要发现。与传统的 PCI 和支架置入相比,ELCA 显示出良好的效果。再灌注时间缩短、微循环增强、术后主要心脏不良事件(MACE)发生率降低,这些都凸显了其疗效。血管和管腔动力学的改善、斑块的修饰以及复杂病变的成功治疗都展示了其多功能性。生活质量的提高对长期康复产生了积极影响,特别是在急性冠状动脉综合症(ACS)病例中。ELCA 在具有挑战性的情况下取得的成功及其在完善支架内再狭窄(ISR)治疗中的作用表明,它的应用范围更加广泛。尽管某些研究存在局限性,但 ELCA 仍具有良好的安全性。综述强调了 ELCA 在冠状动脉介入治疗中的动态作用,为提高手术效果提供了一种前景广阔的工具。其临床意义包括改善再灌注、适应复杂病变以及为 ACS 患者带来潜在的长期益处。虽然将 ELCA 纳入常规治疗需要慎重考虑,但它的积极成果鼓励了介入心脏病学的进一步探索和创新。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Excimer laser coronary angioplasty: a mini-narrative review of clinical outcomes
Excimer laser coronary angioplasty (ELCA) has evolved as a pivotal element in percutaneous coronary intervention (PCI), significantly influencing procedural efficacy and safety. This mini-narrative review explores ELCA's applications, focusing on its efficacy and clinical outcomes. A search of major databases identified studies from ELCA's inception. Inclusion criteria encompassed diverse study designs exploring ELCA in coronary interventions, with rigorous data extraction ensuring accuracy and completeness. A narrative synthesis presented key findings across studies. ELCA demonstrated promising outcomes compared to traditional PCI and stent placement. Reduced reperfusion time, enhanced microcirculation, and lower postoperative major adverse cardiac events (MACE) rates highlighted its efficacy. Improved vascular and lumen dynamics, plaque modification, and successful treatment of complex lesions showcased its versatility. Quality of life enhancements positively impacted long-term recovery, particularly in acute coronary syndrome (ACS) cases. ELCA's success in challenging scenarios and its role in refining in-stent restenosis (ISR) treatment indicated broader applications. Despite limitations in some studies, ELCA presented a favorable safety profile. The review underscores ELCA's dynamic role in coronary interventions, offering a promising tool for enhancing procedural outcomes. Clinical implications include improved reperfusion, adaptability in complex lesions, and potential long-term benefits for ACS patients. While integration into routine practice requires careful consideration, ELCA's positive outcomes encourage further exploration and innovation in interventional cardiology.
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