铜催化β,γ-不饱和肟与二氧化硫和选择氟的氧氟磺酰化反应，制备异噁唑啉官能化脂肪族磺酰氟

IF 3.3 2区化学 Q1 CHEMISTRY, ORGANIC

The Journal of Organic Chemistry Pub Date : 2024-09-19 DOI:10.1021/acs.joc.4c00616

Hui-Jie Du, Lin Qi, Zhi-Min Yan, Jia-Li Liu, Wei Li, Li-Jing Wang

{"title":"铜催化β,γ-不饱和肟与二氧化硫和选择氟的氧氟磺酰化反应，制备异噁唑啉官能化脂肪族磺酰氟","authors":"Hui-Jie Du, Lin Qi, Zhi-Min Yan, Jia-Li Liu, Wei Li, Li-Jing Wang","doi":"10.1021/acs.joc.4c00616","DOIUrl":null,"url":null,"abstract":"In this report, we describe a copper-catalyzed cascade reaction involving oxygen radical-induced cyclization/SO<sub>2</sub> insertion/fluorination of β,γ-unsaturated oximes with sulfur dioxide and Selectfluor under mild conditions for the synthesis of isoxazoline-functionalized aliphatic sulfonyl fluorides. The synthetic potential of these compounds has been evaluated through diverse SuFEx reactions.","PeriodicalId":57,"journal":{"name":"The Journal of Organic Chemistry","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Copper-Catalyzed Oxyfluorosulfonylation of β,γ-Unsaturated Oximes with Sulfur Dioxide and Selectfluor for Isoxazoline-Functionalized Aliphatic Sulfonyl Fluorides\",\"authors\":\"Hui-Jie Du, Lin Qi, Zhi-Min Yan, Jia-Li Liu, Wei Li, Li-Jing Wang\",\"doi\":\"10.1021/acs.joc.4c00616\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this report, we describe a copper-catalyzed cascade reaction involving oxygen radical-induced cyclization/SO<sub>2</sub> insertion/fluorination of β,γ-unsaturated oximes with sulfur dioxide and Selectfluor under mild conditions for the synthesis of isoxazoline-functionalized aliphatic sulfonyl fluorides. The synthetic potential of these compounds has been evaluated through diverse SuFEx reactions.\",\"PeriodicalId\":57,\"journal\":{\"name\":\"The Journal of Organic Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-09-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Organic Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://doi.org/10.1021/acs.joc.4c00616\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Organic Chemistry","FirstCategoryId":"1","ListUrlMain":"https://doi.org/10.1021/acs.joc.4c00616","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}

引用次数: 0

摘要

在本报告中，我们描述了一种铜催化的级联反应，其中涉及氧自由基诱导的β,γ-不饱和肟与二氧化硫和 Selectfluor 在温和条件下的环化/SO2 插入/氟化反应，用于合成异噁唑啉官能化脂肪族磺酰氟。这些化合物的合成潜力已通过多种 SuFEx 反应进行了评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Copper-Catalyzed Oxyfluorosulfonylation of β,γ-Unsaturated Oximes with Sulfur Dioxide and Selectfluor for Isoxazoline-Functionalized Aliphatic Sulfonyl Fluorides

查看原文本刊更多论文

Copper-Catalyzed Oxyfluorosulfonylation of β,γ-Unsaturated Oximes with Sulfur Dioxide and Selectfluor for Isoxazoline-Functionalized Aliphatic Sulfonyl Fluorides

In this report, we describe a copper-catalyzed cascade reaction involving oxygen radical-induced cyclization/SO₂ insertion/fluorination of β,γ-unsaturated oximes with sulfur dioxide and Selectfluor under mild conditions for the synthesis of isoxazoline-functionalized aliphatic sulfonyl fluorides. The synthetic potential of these compounds has been evaluated through diverse SuFEx reactions.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

The Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： The Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.