在 GeneXpert MTB/RIF 超阴性痰中使用 GenoType CMdirect 和 GenoType Mycobacterium CM 线探针检测法鉴定非结核分枝杆菌：南非流行病学研究

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2024-09-10 DOI:10.1016/j.diagmicrobio.2024.116531

Christoffel Opperman , Chaldene Johannes , Sarishna Singh , Yonas Ghebrekristos , Rob Warren , Aliasgar Esmail , Wynand Goosen

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引用次数: 0

摘要

利用 GenoType CMdirect Ver 1.0 和 GenoType 分枝杆菌普通分枝杆菌 Ver 2.0 线探针检测法从 GeneXpert MTB/RIF Ultra 阴性队列中净化的痰液中鉴定非结核分枝杆菌（NTM）。初步观察到的非结核分枝杆菌感染率为 1.7%，特异性为 100%。CMdirect的高特异性证明它可以作为NTM疾病的常规检测方法。

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Identification of nontuberculous mycobacteria using the GenoType CMdirect and GenoType Mycobacterium CM line probe assays in GeneXpert MTB/RIF Ultra negative sputum: A South African prevalence study

The GenoType CMdirect Ver 1.0 and GenoType Mycobacterium Common Mycobacteria Ver 2.0-line probe assays were utilized to identify nontuberculous mycobacteria (NTM) from decontaminated sputum in a GeneXpert MTB/RIF Ultra negative cohort. A preliminary NTM prevalence of 1.7 % was observed, with a 100 % specificity. The high specificity advocates the CMdirect as a possible rule-in test for NTM disease.

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.