越橘（Vaccinium vitis-idaea L.）果实酚类生物活性--体外和体内人体研究综述

IF 4.1 2区生物学 Q2 MICROBIOLOGY

Microorganisms Pub Date : 2024-09-06 DOI:10.3390/microorganisms12091850

Pirjo Pärnänen, Sari Niikko, Hanna Lähteenmäki, Ismo T. Räisänen, Taina Tervahartiala, Timo Sorsa, Annamari Ranki

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引用次数: 0

摘要

本综述侧重于越橘（Vaccinium vitis-idaea L.）果实酚类化合物在人体体外细胞和体内临床研究中的作用。综述了有关越橘、越橘汁/越橘花蜜/发酵越橘汁以及含有活性分子的酚类组分的研究。越橘的生物活性物质具有抗菌、消炎、抗蛋白溶解、抗癌和抗氧化等多种特性。研究还讨论了越橘的发酵以及通过促进乳酸菌的生长和抑制人类机会性病原体的生长，将菌群失调的微生物组调节为更加共生的组成。研究结果表明，需要对人类进行更多的研究。

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Lingonberry (Vaccinium vitis-idaea L.) Fruit Phenolic Bioactivities—A Review of In Vitro and In Vivo Human Studies

This review is focused on the effects of lingonberry (Vaccinium vitis-idaea L.) fruit phenolic compounds in human in vitro cells and in vivo clinical studies. Studies with lingonberries, lingonberry juice/lingonberry nectar/fermented lingonberry juice, and phenolic fractions with active molecules are reviewed. Lingonberry’s bioactive substances have a diverse range of antimicrobial, anti-inflammatory, antiproteolytic, anticancer, and antioxidant properties. Fermentation of lingonberries and modulation of the dysbiotic microbiome to a more symbiotic composition by favoring the growth of lactobacilli and inhibiting the growth of human opportunistic pathogens are discussed. Research results suggest that more studies on humans are needed.

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来源期刊

Microorganisms Medicine-Microbiology (medical)

CiteScore

7.40

自引率

6.70%

发文量

2168

审稿时长

20.03 days

期刊介绍： Microorganisms (ISSN 2076-2607) is an international, peer-reviewed open access journal which provides an advanced forum for studies related to prokaryotic and eukaryotic microorganisms, viruses and prions. It publishes reviews, research papers and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.