用 β-三氟甲基丙烯酸酯合成三氟甲基取代的杂环化合物

IF 1.8 3区化学 Q3 CHEMISTRY, ORGANIC

Synthetic Communications Pub Date : 2024-08-10 DOI:10.1080/00397911.2024.2390696

Cai Zhang

引用次数: 0

摘要

三氟甲基杂环化合物具有很高的亲脂性、代谢稳定性和结合选择性，因此开发其合成方法非常重要。本综述介绍了...

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Synthesis of trifluoromethyl substituted heterocyclic compounds with β-trifluoromethylated acrylates

Trifluoromethyl heterocyclic compounds have high lipophilicity, metabolic stability and binding selectivity, so it is very important to develop their synthetic methods. This review provides an overview of synthesis of trifluoromethyl substituted heterocyclic compounds from β-trifluoromethylated acrylates over the period from 2018 to the present.

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来源期刊

Synthetic Communications 化学-有机化学

CiteScore

4.40

自引率

4.80%

发文量

156

审稿时长

4.3 months

期刊介绍： Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.