关于估算疫苗疗效的一些模型问题

IF 1.3 4区医学 Q4 PHARMACOLOGY & PHARMACY

Pharmaceutical Statistics Pub Date : 2024-09-10 DOI:10.1002/pst.2440

Mauro Gasparini

引用次数: 0

摘要

我想重新考虑一下森教授最近对辉瑞-生物技术公司疫苗试验统计的分析，发表一些不同的看法，并澄清一些理论观点，特别是关于贝叶斯统计的临床应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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On Some Modeling Issues in Estimating Vaccine Efficacy

I would like to reconsider a recent analysis by Prof. Senn on the statistics of the Pfizer‐BioNTech vaccine trial, to express some different opinions and to clarify some theoretical points, especially regarding the clinical applications of Bayesian statistics.

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来源期刊

Pharmaceutical Statistics 医学-统计学与概率论

CiteScore

2.70

自引率

6.70%

发文量

审稿时长

6-12 weeks

期刊介绍： Pharmaceutical Statistics is an industry-led initiative, tackling real problems in statistical applications. The Journal publishes papers that share experiences in the practical application of statistics within the pharmaceutical industry. It covers all aspects of pharmaceutical statistical applications from discovery, through pre-clinical development, clinical development, post-marketing surveillance, consumer health, production, epidemiology, and health economics. The Journal is both international and multidisciplinary. It includes high quality practical papers, case studies and review papers.