促进健康的蠕虫？蠕虫疗法的前景与陷阱

IF 3.2 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

BioEssays Pub Date : 2024-09-12 DOI:10.1002/bies.202400080

Ingrid Lamminpää, Federico Boem, Amedeo Amedei

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引用次数: 0

摘要

在本手稿中，我们探讨了螺旋虫的潜在治疗用途。在从共生和进化关系的角度分析蠕虫在人类健康中的作用后，我们对有关其治疗应用的一些研究进行了批判性审视。在此过程中，我们关注了一些突出的作用机制和潜在益处，同时也关注了这些建议的夸大之处以及理论和方法上的困难。我们的结论是，还需要进一步的研究来充分探索这一观点的潜在益处，并鼓励科学界这样做。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Health-promoting worms? Prospects and pitfalls of helminth therapy

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Health-promoting worms? Prospects and pitfalls of helminth therapy

In this manuscript, we explore the potential therapeutic use of helminths. After analyzing helminths’ role in connection with human health from the perspective of their symbiotic and evolutionary relationship, we critically examine some studies on their therapeutic applications. In doing so, we focus on some prominent mechanisms of action and potential benefits, but also on the exaggerations and theoretical and methodological difficulties of such proposals. We conclude that further studies are needed to fully explore the potential benefits of this perspective, and we encourage the scientific community in doing so.

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来源期刊

BioEssays 生物-生化与分子生物学

CiteScore

7.30

自引率

2.50%

发文量

167

审稿时长

4-8 weeks

期刊介绍： molecular – cellular – biomedical – physiology – translational research – systems - hypotheses encouraged BioEssays is a peer-reviewed, review-and-discussion journal. Our aims are to publish novel insights, forward-looking reviews and commentaries in contemporary biology with a molecular, genetic, cellular, or physiological dimension, and serve as a discussion forum for new ideas in these areas. An additional goal is to encourage transdisciplinarity and integrative biology in the context of organismal studies, systems approaches, through to ecosystems, where appropriate.