人类子宫内膜周细胞：子宫内膜周细胞的生理功能及其对子宫疾病的影响综述

IF 5.1 2区生物学 Q2 CELL BIOLOGY

Cells Pub Date : 2024-09-09 DOI:10.3390/cells13171510

Yiqun Tang, Caroline Frisendahl, Terhi T. Piltonen, Riikka K. Arffman, Parameswaran Grace Lalitkumar, Kristina Gemzell-Danielsson

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引用次数: 0

摘要

周细胞是微循环血管壁上不可或缺的多功能细胞，它们表现出特定的干细胞特征。它们在调节血流、确保血管通透性、维持平衡和参与组织修复过程方面至关重要。人类子宫内膜是一种独特而复杂的组织，它是一种天然的无疤痕愈合模型，每个月都有周期性的修复和再生过程。由于周细胞参与了各种生理和病理过程，其调控作用日益受到关注。然而，与其他器官的周细胞相比，对子宫内膜周细胞的研究较少。本综述旨在全面概述子宫内膜周细胞，重点阐明其生理功能以及对子宫疾病的潜在影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Human Endometrial Pericytes: A Comprehensive Overview of Their Physiological Functions and Implications in Uterine Disorders

Pericytes are versatile cells integral to the blood vessel walls of the microcirculation, where they exhibit specific stem cell traits. They are essential in modulating blood flow, ensuring vascular permeability, and maintaining homeostasis and are involved in the tissue repair process. The human endometrium is a unique and complex tissue that serves as a natural scar-free healing model with its cyclical repair and regeneration process every month. The regulation of pericytes has gained increasing attention due to their involvement in various physiological and pathological processes. However, endometrial pericytes are less well studied compared to the pericytes in other organs. This review aims to provide a comprehensive overview of endometrial pericytes, with a focus on elucidating their physiological function and potential implications in uterine disorders.

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来源期刊

Cells Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

9.90

自引率

5.00%

发文量

3472

审稿时长

16 days

期刊介绍： Cells (ISSN 2073-4409) is an international, peer-reviewed open access journal which provides an advanced forum for studies related to cell biology, molecular biology and biophysics. It publishes reviews, research articles, communications and technical notes. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. Full experimental and/or methodical details must be provided.