用于肿瘤光疗的上转换纳米材料的研究进展

IF 3.7 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Today Communications Pub Date : 2024-09-03 DOI:10.1016/j.mtcomm.2024.110301

Shunuo Bian, Wenqiang Lu, Lin Zhou, Tao Jin

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引用次数: 0

摘要

肿瘤是人类疾病的主要致死原因，肿瘤治疗的相关研究迫在眉睫。光疗能以无创、微创的方式实现肿瘤的精确定位和靶向清除，具有巨大的临床应用潜力。上转换纳米粒子（UCNPs）不仅可以解决目前光疗对深部组织肿瘤根除有限的问题，还具有稳定性好、寿命长、生物毒性低等优点。本文综述了光疗的基础研究现状以及 UCNPs 纳米复合材料在光疗中的作用机理和应用进展。综述重点介绍了 UCNPs 纳米复合材料的结构和组成调控方法，为 UCNPs 纳米复合材料在光疗中的应用设计提供了关键点和解决方案，并对该领域的研究和发展进行了展望。

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Advances in upconversion nanomaterials for tumor phototherapy

Tumor is the main cause of death in human diseases, and the related research on tumor treatment is imminent. Phototherapy can achieve precise positioning and targeted removal of tumors in a non-invasive and minimally invasive manner, which has great potential for clinical application. Upconversion nanoparticles(UCNPs) can not only solve the problem of limited eradication of deep tissue tumors in current phototherapy, but also have the advantages of good stability, long life span and low biotoxicity. This article reviews the basic research status of phototherapy and the mechanism and application progress of UCNPs nanocomposites in phototherapy. This review focuses on the structure and composition regulation methods of UCNPs nanocomposites, which provides key points and solutions for the application design of UCNPs nanocomposites in phototherapy, and prospects the research and development in this field.

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来源期刊

Materials Today Communications Materials Science-General Materials Science

CiteScore

5.20

自引率

5.30%

发文量

1783

审稿时长

51 days

期刊介绍： Materials Today Communications is a primary research journal covering all areas of materials science. The journal offers the materials community an innovative, efficient and flexible route for the publication of original research which has not found the right home on first submission.