吲哚的催化硫代甲基化反应

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2024-08-31 DOI:10.1007/s11172-024-4315-6

V. R. Akhmetova, D. V. Leont’ev, N. S. Akhmadiev, E. A. Paramonov

{"title":"吲哚的催化硫代甲基化反应","authors":"V. R. Akhmetova, D. V. Leont’ev, N. S. Akhmadiev, E. A. Paramonov","doi":"10.1007/s11172-024-4315-6","DOIUrl":null,"url":null,"abstract":"The catalysis of direct thiomethylation of 1H-indole and tryptophan under the action of the formaldehyde—mercaptan reagent system in the presence of acids and bases, phosphorus oxide and the oxidative system I2/NaOH was studied. A mechanism for the catalysis of the multicomponent thiomethylation reaction was proposed based on the results of mass spectrometric study of intermediate compounds.","PeriodicalId":756,"journal":{"name":"Russian Chemical Bulletin","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Catalytic thiomethylation of indoles\",\"authors\":\"V. R. Akhmetova, D. V. Leont’ev, N. S. Akhmadiev, E. A. Paramonov\",\"doi\":\"10.1007/s11172-024-4315-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The catalysis of direct thiomethylation of 1H-indole and tryptophan under the action of the formaldehyde—mercaptan reagent system in the presence of acids and bases, phosphorus oxide and the oxidative system I2/NaOH was studied. A mechanism for the catalysis of the multicomponent thiomethylation reaction was proposed based on the results of mass spectrometric study of intermediate compounds.\",\"PeriodicalId\":756,\"journal\":{\"name\":\"Russian Chemical Bulletin\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-08-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Chemical Bulletin\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1007/s11172-024-4315-6\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Chemical Bulletin","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s11172-024-4315-6","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

研究了在酸和碱、氧化磷以及 I2/NaOH 氧化体系存在下，甲醛-硫醇试剂体系对 1H-indole 和色氨酸直接硫代甲基化反应的催化作用。根据中间化合物的质谱研究结果，提出了多组分硫代甲基化反应的催化机理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Catalytic thiomethylation of indoles

The catalysis of direct thiomethylation of 1H-indole and tryptophan under the action of the formaldehyde—mercaptan reagent system in the presence of acids and bases, phosphorus oxide and the oxidative system I₂/NaOH was studied. A mechanism for the catalysis of the multicomponent thiomethylation reaction was proposed based on the results of mass spectrometric study of intermediate compounds.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.