使用干基质斑点作为监测被忽视热带病的替代采样技术

IF 3.3 3区 医学 Q2 MICROBIOLOGY
Wanesa Richert, Krzysztof Korzeniewski
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引用次数: 0

摘要

被忽视的热带疾病(NTDs)是一组通常表现为慢性临床症状的疾病。NTD 可导致永久性残疾,而且往往与社会耻辱联系在一起。在许多 NTD 流行的发展中国家,没有安全储存和运输生物样本的诊断工具,也没有可以处理样本的专业诊断中心。将在野外采集的生物样本(血液、尿液)运送到发达国家的实验室需要在运输过程中保持冷链。确保运输过程中的温度控制可能是个问题,甚至是不可能实现的,而且成本高昂。解决这一问题的有效方法是使用干燥基质斑点(DMS)技术,该技术似乎是收集生物样本用于发展中国家非传染性疾病筛查和流行病学监测的可靠方法。本文概述了如何将干基质点用于诊断大多数被忽视的热带疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Use of Dried Matrix Spots as an Alternative Sampling Technique for Monitoring Neglected Tropical Diseases
Neglected tropical diseases (NTDs) are a group of illnesses which usually present with a chronic clinical picture. NTDs can lead to permanent disability and are often associated with social stigma. In many developing countries where NTDs are endemic, there are no diagnostic tools for the safe storage and transport of biological samples, and there are no specialist diagnostic centers where the samples could be processed. The transport of biological samples (blood, urine) collected in field conditions and brought to laboratories located in developed countries requires the maintenance of the cold chain during transportation. Ensuring temperature control during transport could be problematic or even impossible to achieve; it is also expensive. A helpful solution to this problem is to use the dried matrix spot (DMS) technique, which seems to be a reliable method for collecting biological samples to be used for screening purposes and conducting epidemiological surveillance of NTDs in developing countries. This article is an overview of how DMSs can be used in the diagnosis of most neglected tropical diseases.
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来源期刊
Pathogens
Pathogens Medicine-Immunology and Allergy
CiteScore
6.40
自引率
8.10%
发文量
1285
审稿时长
17.75 days
期刊介绍: Pathogens (ISSN 2076-0817) publishes reviews, regular research papers and short notes on all aspects of pathogens and pathogen-host interactions. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodical details must be provided for research articles.
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