西孟加拉邦孟加拉族人群中 PNPLA3 的 rs738409 多态性与非酒精性脂肪肝的发展和严重程度的关系

Mousumi Das, Arindam Biswas, Soumik Goswami, Rajat Deb, Sukdeb Das, Debes Ray
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引用次数: 0

摘要

背景和目的 非酒精性脂肪肝(NAFLD)是一种常见疾病,病因复杂。据报道,在一些种族人群中,PNPLA3 基因的多态性变异 rs738409(Ile148Met)与非酒精性脂肪肝相关。本研究旨在确定该 PNPLA3 基因变异与西孟加拉邦孟加拉族非酒精性脂肪肝的潜在关联,并将其与疾病严重程度和生化指标相关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association of the rs738409 polymorphism in PNPLA3 with development and severity of non-alcoholic fatty liver disease in ethnic Bengali population of West Bengal
Background and Objectives Non-alcoholic Fatty Liver Disease (NAFLD) is a common disorder with a complex etiology. Polymorphic variant rs738409 (Ile148Met) in the PNPLA3 gene has been reported to be associated with NAFLD among several ethnic populations. The present study aims to identify the potential association of this PNPLA3 gene variant with NAFLD among the ethnic Bengali population of West Bengal and correlate it with disease severity and biochemical parameters.
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