DNA 损伤在糖尿病并发症中的作用

IF 3.7 3区医学 Q2 CHEMISTRY, MEDICINAL

Chemical Research in Toxicology Pub Date : 2024-09-12 DOI:10.1038/s41574-024-01038-z

Varun Kumar, Ali Önder Yildirim, Peter P. Nawroth

引用次数: 0

摘要

机理和临床数据表明，DNA 损伤是糖尿病并发症发病和恶化的原因之一。因此，DNA 损伤及其信号正在进入糖尿病学领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The role of DNA damage in diabetic complications

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The role of DNA damage in diabetic complications

Mechanistic and clinical data indicate that DNA damage contributes to the pathogenesis and progression of diabetic complications. Thus, DNA damage and its signalling are entering the field of diabetology.

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来源期刊

Chemical Research in Toxicology 医学-毒理学

CiteScore

7.90

自引率

7.30%

发文量

215

审稿时长

3.5 months

期刊介绍： Chemical Research in Toxicology publishes Articles, Rapid Reports, Chemical Profiles, Reviews, Perspectives, Letters to the Editor, and ToxWatch on a wide range of topics in Toxicology that inform a chemical and molecular understanding and capacity to predict biological outcomes on the basis of structures and processes. The overarching goal of activities reported in the Journal are to provide knowledge and innovative approaches needed to promote intelligent solutions for human safety and ecosystem preservation. The journal emphasizes insight concerning mechanisms of toxicity over phenomenological observations. It upholds rigorous chemical, physical and mathematical standards for characterization and application of modern techniques.