Shao-Hua Zhuo, Tian-Yang Wang, Lang Zhao, Jing-Yun Su, Jin-Jian Hu, Yu-Fen Zhao, Yan-Mei Li
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Rücktitelbild: piSTING: A Pocket-Independent Agonist Based on Multivalency-Driven STING Oligomerization (Angew. Chem. 38/2024)
Novel pocket-independent STING-activating agonists (piSTINGs), which act through multivalency-driven oligomerization to activate downstream signalling pathways, were developed by Yan-Mei Li et al. in their Research Article (e202407037). piSTINGs could serve as novel STING agonists for vaccines and combination therapies. STING oligomerization is a useful strategy for the development of a new generation of STING agonists.
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