基于纳米技术的抗菌疗法

IF 6 2区 医学 Q1 CHEMISTRY, MEDICINAL
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引用次数: 0

摘要

抗菌治疗技术的作用是阻止或减缓可杀死人、动物和农作物的细菌的生长。最广泛使用的抗菌剂是抗生素。尽管这些抗菌药物相当有效,但在有效使用过程中仍存在一些障碍或挑战。为了解决这些问题,我们需要没有副作用或抗药性的新型抗菌药物分子。如今,将抗菌药物置于由不同金属和金属氧化物以及聚合物、碳或脂基制成的纳米级载体(或称纳米药物)中,可用于解决传统疗法和给药技术的这些问题。本综述重点介绍纳米技术在抗菌治疗中的重要性、用于这种治疗的纳米颗粒(NPs)、其作用模式以及纳米技术在抗菌治疗中的最新进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Nanotechnology-based approaches for antibacterial therapy

Nanotechnology-based approaches for antibacterial therapy

The technique of antimicrobial therapy action is to stop or slow the growth of bacteria that can kill people, animals, and crops. The most widely used antibacterial agents are antibiotics. Even though these antimicrobial medications are quite effective, there are still certain barriers or challenges in using them effectively. To solve these issues, new antimicrobial drug molecules that don't have side effects or resistance are needed. These days, antimicrobial drugs placed in nanosized vehicles, or nanomedicine, made of different metal and metallic oxides as well as of polymer, carbon or lipid-based may be used to address these issues with conventional therapy and delivery techniques. This review focuses on the importance of nanotechnology in antimicrobial therapy, nanoparticles (NPs) used in this therapy, their mode of action, and the recent advancement in nanotechnology for antimicrobial therapy.

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来源期刊
CiteScore
11.70
自引率
9.00%
发文量
863
审稿时长
29 days
期刊介绍: The European Journal of Medicinal Chemistry is a global journal that publishes studies on all aspects of medicinal chemistry. It provides a medium for publication of original papers and also welcomes critical review papers. A typical paper would report on the organic synthesis, characterization and pharmacological evaluation of compounds. Other topics of interest are drug design, QSAR, molecular modeling, drug-receptor interactions, molecular aspects of drug metabolism, prodrug synthesis and drug targeting. The journal expects manuscripts to present the rational for a study, provide insight into the design of compounds or understanding of mechanism, or clarify the targets.
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