藻酸盐凝胶作为肿瘤给药载体在肿瘤定位和三维肿瘤细胞模型中的应用研究进展

Lili Huang , Yicong Lei , Yucheng Chen , Xin Hu , Chengyu Huang , Huaqing Lin
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引用次数: 0

摘要

作为生物医学研究的热点材料之一,海藻酸盐凝胶以其独特的物理和化学性质在肿瘤治疗中显示出巨大的潜力。为了更好地满足肿瘤治疗的复杂需求,海藻酸盐凝胶复合体系应运而生。该体系不仅继承了单一海藻酸盐凝胶的诸多优点,还通过复合显著提高了材料的机械性能,有效克服了应用的局限性。这些复合材料已以多种形式应用于药物输送载体、肿瘤靶向系统和三维肿瘤细胞模型等领域,展现出广泛的应用前景。本文旨在回顾海藻酸凝胶的基本结构和性能,分析近年来海藻酸凝胶复合材料体系在肿瘤领域的研究进展,为进一步拓展该材料在肿瘤治疗中的应用提供有价值的参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Research progress in application of alginate gel as tumor drug delivery carrier, for tumor localization and 3D tumor cell model

As one of the hot materials in biomedical research, alginate gel shows great potential in tumor therapy with its unique physical and chemical properties. In order to better meet the complex needs of cancer treatment, alginate brine gel composite system has come into being. This system not only inherits many advantages of single alginate brine gel, but also significantly improves the mechanical properties of the material through compounding, and effectively overcomes the limitations of application. These composites have been applied to drug delivery carriers, tumor targeting systems and three-dimensional tumor cell models in various forms, showing a wide range of application prospects. This paper aims to review the basic structure and properties of alginate gel and analyze the research progress of alginate gel composite systems in the field of cancer in recent years, to provide a valuable reference for the further expansion of the application of this material in tumor therapy.

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