Tingting Han , Chen Cui , Yujun Xing , Jianrong Shi , Jianhong Xu , Jun-Jie Zhu
{"title":"霉菌毒素电化学发光传感器的信号放大策略和传感形式的进展","authors":"Tingting Han , Chen Cui , Yujun Xing , Jianrong Shi , Jianhong Xu , Jun-Jie Zhu","doi":"10.1016/j.trac.2024.117961","DOIUrl":null,"url":null,"abstract":"<div><p>Mycotoxins are toxic secondary metabolites produced by fungus, which has carcinogenicity, teratogenicity, mutagenicity, and immunotoxicity, posing a serious hazard to food safety and public health. Therefore, it is of great importance to exploit rapid, sensitive, and universal analytical methods for mycotoxins detection to safeguard food safety and public health. Electrochemiluminescence (ECL) has been regarded as a promising analytical technology for monitoring mycotoxins in foods due to zero background and high sensitivity. Signal amplification strategies take vital roles in developing advanced ECL biosensors with high sensitiveness. Besides, deep insights into sensing formats and patterns will favour in designing innovative ECL sensors. In this review, the latest developments in various ECL sensors for mycotoxins assays are summarized, with emphasis on signal enhancement strategies and sensing formats in their applications. The opportunities and challenges are also discussed in the development and application of advanced ECL sensors for mycotoxins analysis.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"180 ","pages":"Article 117961"},"PeriodicalIF":11.8000,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Advances of signal amplification strategies and sensing formats in electrochemiluminescence sensors for mycotoxins\",\"authors\":\"Tingting Han , Chen Cui , Yujun Xing , Jianrong Shi , Jianhong Xu , Jun-Jie Zhu\",\"doi\":\"10.1016/j.trac.2024.117961\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Mycotoxins are toxic secondary metabolites produced by fungus, which has carcinogenicity, teratogenicity, mutagenicity, and immunotoxicity, posing a serious hazard to food safety and public health. Therefore, it is of great importance to exploit rapid, sensitive, and universal analytical methods for mycotoxins detection to safeguard food safety and public health. Electrochemiluminescence (ECL) has been regarded as a promising analytical technology for monitoring mycotoxins in foods due to zero background and high sensitivity. Signal amplification strategies take vital roles in developing advanced ECL biosensors with high sensitiveness. Besides, deep insights into sensing formats and patterns will favour in designing innovative ECL sensors. In this review, the latest developments in various ECL sensors for mycotoxins assays are summarized, with emphasis on signal enhancement strategies and sensing formats in their applications. The opportunities and challenges are also discussed in the development and application of advanced ECL sensors for mycotoxins analysis.</p></div>\",\"PeriodicalId\":439,\"journal\":{\"name\":\"Trends in Analytical Chemistry\",\"volume\":\"180 \",\"pages\":\"Article 117961\"},\"PeriodicalIF\":11.8000,\"publicationDate\":\"2024-09-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Analytical Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0165993624004448\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993624004448","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Advances of signal amplification strategies and sensing formats in electrochemiluminescence sensors for mycotoxins
Mycotoxins are toxic secondary metabolites produced by fungus, which has carcinogenicity, teratogenicity, mutagenicity, and immunotoxicity, posing a serious hazard to food safety and public health. Therefore, it is of great importance to exploit rapid, sensitive, and universal analytical methods for mycotoxins detection to safeguard food safety and public health. Electrochemiluminescence (ECL) has been regarded as a promising analytical technology for monitoring mycotoxins in foods due to zero background and high sensitivity. Signal amplification strategies take vital roles in developing advanced ECL biosensors with high sensitiveness. Besides, deep insights into sensing formats and patterns will favour in designing innovative ECL sensors. In this review, the latest developments in various ECL sensors for mycotoxins assays are summarized, with emphasis on signal enhancement strategies and sensing formats in their applications. The opportunities and challenges are also discussed in the development and application of advanced ECL sensors for mycotoxins analysis.
期刊介绍：
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.
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