{"title":"腰椎管狭窄症患者脑脊液中的蛋白质浓度。","authors":"Hitoshi Yamahata, Kosei Ijiri, Fumito Tanabe, Kyoichi Murasumi, Yushi Nagano, Ryutaro Makino, Nayuta Higa, Ryosuke Hanaya","doi":"10.25259/SNI_610_2024","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>In this study, we examined the impact and degree of lumbar stenosis on cerebrospinal fluid (CSF) protein concentration.</p><p><strong>Methods: </strong>In this retrospective study, we analyzed protein concentrations in CSF samples of 61 patients with lumbar spinal stenosis (LSS) obtained during pre-operative myelography. Patients were divided into two groups: those showing no block to contrast (Group A) versus those showing medium block to contrast below the lumbar puncture level (Group B).</p><p><strong>Results: </strong>The CSF protein concentration in Group B (104.3 ± 59 g/dL) patients with medium block was significantly greater than that in Group A (65.1 ± 33 g/dL) patients without medium block.</p><p><strong>Conclusion: </strong>A higher average CSF protein concentration was seen in Group B patients with significant lumbar stenosis versus Group A patients without significant lumbar stenosis. Theoretically, damage to the cauda equina in patients with LSS may cause these elevated CSF protein levels.</p>","PeriodicalId":94217,"journal":{"name":"Surgical neurology international","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11380900/pdf/","citationCount":"0","resultStr":"{\"title\":\"Cerebrospinal fluid protein concentration in patients with lumbar spinal stenosis.\",\"authors\":\"Hitoshi Yamahata, Kosei Ijiri, Fumito Tanabe, Kyoichi Murasumi, Yushi Nagano, Ryutaro Makino, Nayuta Higa, Ryosuke Hanaya\",\"doi\":\"10.25259/SNI_610_2024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>In this study, we examined the impact and degree of lumbar stenosis on cerebrospinal fluid (CSF) protein concentration.</p><p><strong>Methods: </strong>In this retrospective study, we analyzed protein concentrations in CSF samples of 61 patients with lumbar spinal stenosis (LSS) obtained during pre-operative myelography. Patients were divided into two groups: those showing no block to contrast (Group A) versus those showing medium block to contrast below the lumbar puncture level (Group B).</p><p><strong>Results: </strong>The CSF protein concentration in Group B (104.3 ± 59 g/dL) patients with medium block was significantly greater than that in Group A (65.1 ± 33 g/dL) patients without medium block.</p><p><strong>Conclusion: </strong>A higher average CSF protein concentration was seen in Group B patients with significant lumbar stenosis versus Group A patients without significant lumbar stenosis. Theoretically, damage to the cauda equina in patients with LSS may cause these elevated CSF protein levels.</p>\",\"PeriodicalId\":94217,\"journal\":{\"name\":\"Surgical neurology international\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11380900/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgical neurology international\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25259/SNI_610_2024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical neurology international","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25259/SNI_610_2024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景：我们研究了腰椎管狭窄对脑脊液（CSF）蛋白浓度的影响和程度：在这项研究中，我们探讨了腰椎管狭窄对脑脊液（CSF）蛋白质浓度的影响和程度：在这项回顾性研究中，我们分析了 61 名腰椎管狭窄（LSS）患者在术前脊髓造影术中获得的 CSF 样本中的蛋白质浓度。患者被分为两组：造影剂无阻滞组（A 组）和腰椎穿刺水平以下造影剂中等阻滞组（B 组）：结果：中度阻滞 B 组患者的 CSF 蛋白浓度（104.3 ± 59 g/dL）明显高于无中度阻滞 A 组患者的 CSF 蛋白浓度（65.1 ± 33 g/dL）：结论：有明显腰椎管狭窄的 B 组患者的 CSF 蛋白平均浓度高于无明显腰椎管狭窄的 A 组患者。从理论上讲，腰椎管狭窄症患者的马尾受损可能会导致 CSF 蛋白水平升高。
Cerebrospinal fluid protein concentration in patients with lumbar spinal stenosis.
Background: In this study, we examined the impact and degree of lumbar stenosis on cerebrospinal fluid (CSF) protein concentration.
Methods: In this retrospective study, we analyzed protein concentrations in CSF samples of 61 patients with lumbar spinal stenosis (LSS) obtained during pre-operative myelography. Patients were divided into two groups: those showing no block to contrast (Group A) versus those showing medium block to contrast below the lumbar puncture level (Group B).
Results: The CSF protein concentration in Group B (104.3 ± 59 g/dL) patients with medium block was significantly greater than that in Group A (65.1 ± 33 g/dL) patients without medium block.
Conclusion: A higher average CSF protein concentration was seen in Group B patients with significant lumbar stenosis versus Group A patients without significant lumbar stenosis. Theoretically, damage to the cauda equina in patients with LSS may cause these elevated CSF protein levels.
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