卵母细胞的健康和质量:线粒体相关细胞器相互作用的影响

Q4 Biochemistry, Genetics and Molecular Biology
Osamu Udagawa
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引用次数: 0

摘要

在荷尔蒙失调和子宫状况等因素中,卵母细胞质量被认为是生殖能力因年龄增长而下降的关键因素之一。这里讨论的是卵母细胞内的细胞器在形成更适合生存的下一代时所发挥的功能。线粒体和其他细胞器之间的相互作用使原始卵母细胞的寿命得以延长;从原始卵母细胞到成熟卵母细胞打破休眠后细胞器之间相互作用的特点;以及从老年个体和动物的排卵周期中收集的老年卵母细胞的线粒体和其他细胞器之间相互作用的特点。这些信息可能有助于未来治疗方法或药物的开发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Oocyte Health and Quality: Implication of Mitochondria-related Organelle Interactions.

Among factors like hormonal imbalance and uterine condition, oocyte quality is regarded as one of the key factors involved in age-related decline in the reproductive capacity. Here, are discussions about the functions played by organelles within the oocyte in forming the next generation that is more suitable for survival. Many insights on the adaptation to aging and maintenance of quality can be obtained from: interactions between mitochondria and other organelles that enable the long life of primordial oocytes; characteristics of organelle interactions after breaking dormancy from primary oocytes to mature oocytes; and characteristics of interactions between mitochondria and other organelles of aged oocytes collected during the ovulatory cycle from elderly individuals and animals. This information would potentially be beneficial to the development of future therapeutic methods or agents.

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来源期刊
Results and Problems in Cell Differentiation
Results and Problems in Cell Differentiation Biochemistry, Genetics and Molecular Biology-Developmental Biology
CiteScore
1.90
自引率
0.00%
发文量
21
期刊介绍: Results and Problems in Cell Differentiation is an up-to-date book series that presents and explores selected questions of cell and developmental biology. Each volume focuses on a single, well-defined topic. Reviews address basic questions and phenomena, but also provide concise information on the most recent advances. Together, the volumes provide a valuable overview of this exciting and dynamically expanding field.
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