静脉血栓栓塞抗凝治疗的持续时间。

IF 3.2 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

Presse Medicale Pub Date : 2024-09-01 DOI:10.1016/j.lpm.2024.104245

Francis Couturaud , Nicolas Meneveau , Marie Antoinette Sevestre , Pierre-Emmanuel Morange , David Jimenez

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引用次数: 0

摘要

静脉血栓栓塞症（VTE）是一种常见的严重疾病，需要至少三个月的抗凝治疗，以防止复发和长期并发症。在这一初始阶段之后，是否继续或停止抗凝取决于复发 VTE 的风险和出血风险之间的平衡。既定指南建议，对于由短暂性因素引起的 VTE，应进行短期抗凝治疗；对于复发性或癌症相关性 VTE，则应进行无限期抗凝治疗。然而，对于首次发生的无诱因 VTE，决策仍具有挑战性。目前的复发和出血预测评分不够可靠，减量抗凝的安全性和有效性仍不明确。未来，精准医学和以患者为中心的医学可能会改善这方面的治疗决策。

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Duration of anticoagulation of venous thromboembolism

Venous thromboembolism (VTE) is a common, serious condition that requires anticoagulation for at least three months to prevent recurrence and long-term complications. After this initial period, the decision to continue or stop anticoagulation depends on the balance between the risk of recurrent VTE and the risk of bleeding. Established guidelines suggest short-term anticoagulation for VTE caused by transient factors and indefinite anticoagulation for recurrent or cancer-associated VTE. However, for a first unprovoked VTE, decision-making remains challenging. Current predictive scores for recurrence and bleeding are not sufficiently reliable, and the safety and efficacy of reduced-dose anticoagulation remain unclear. In the future, precision and patient-centred medicine may improve treatment decisions in this area.

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来源期刊

Presse Medicale 医学-医学：内科

自引率

3.70%

发文量

审稿时长

43 days

期刊介绍： Seule revue médicale "généraliste" de haut niveau, La Presse Médicale est l''équivalent francophone des grandes revues anglosaxonnes de publication et de formation continue. A raison d''un numéro par mois, La Presse Médicale vous offre une double approche éditoriale : - des publications originales (articles originaux, revues systématiques, cas cliniques) soumises à double expertise, portant sur les avancées médicales les plus récentes ; - une partie orientée vers la FMC, vous propose une mise à jour permanente et de haut niveau de vos connaissances, sous forme de dossiers thématiques et de mises au point dans les principales spécialités médicales, pour vous aider à optimiser votre formation.