对出现高度吞咽困难的患者进行诊室内经鼻食道镜检查和球囊扩张术的有效性和安全性：6 年回顾性分析。

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY

Clinical Otolaryngology Pub Date : 2024-09-05 DOI:10.1111/coa.14222

Chang Woo Lee, Virginia Fancello, Alex Dando, Fenella Bennett, Virginia Ludwig, Kate J. Heathcote

引用次数: 0

摘要

研究背景本研究的主要目的是评估诊室内经鼻食道镜检查（TNO）和球囊扩张术对出现高度吞咽困难症状患者的疗效和安全性。次要目标是进行亚组分析，以更好地了解患者的选择情况：方法：对一家大学医院进行回顾性观察研究：共为 146 名患者（中位年龄 73 岁；范围 12-94 岁）实施了 244 例 TNO 和球囊扩张术。适应症包括环咽肥大±囊肿（70 例）、下咽/上食道网状结构/狭窄（18 例）、头颈部癌症治疗相关（41 例）、多层次梗阻（13 例）和症状性梗阻（4 例）。EAT-10平均得分从扩张前的21.2（标度±8.92）分提高到扩张后的12.6（标度±10.7）分（中位随访时间为4.4个月；范围为1.5个月至6.21年）。环咽肥大和/或无运动障碍的网络组反应最好，EAT-10评分平均值从20.4（标准差±8.21）分提高到4.4（标准差±6.71）分。头颈部癌症患者组显示出三种反应：反应良好，但效果短暂，需要重复扩张；最初反应良好，但随着时间推移停止反应；无反应。总体并发症发生率为 0.98%（n = 2/204；均在门诊尝试失败），穿孔率为 0%：TNO和球囊扩张术是一种安全有效的治疗方式，可用于治疗食管上括约肌水平及其周围可识别的非恶性阻塞性病变患者（包括头颈部癌症治疗相关患者）的高度吞咽困难，无论是短期还是长期。吞钡是评估整体吞咽情况的绝佳筛查工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Efficacy and Safety of In-Office Transnasal Oesophagoscopy and Balloon Dilatation for Patients Presenting With High Dysphagia: A 6-Year Retrospective Analysis

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Efficacy and Safety of In-Office Transnasal Oesophagoscopy and Balloon Dilatation for Patients Presenting With High Dysphagia: A 6-Year Retrospective Analysis

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来源期刊

Clinical Otolaryngology 医学-耳鼻喉科学

CiteScore

4.00

自引率

4.80%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.