{"title":"托吡酯与纳曲酮相比，在治疗酒精使用障碍方面效果更佳","authors":"","doi":"10.1002/pu.31213","DOIUrl":null,"url":null,"abstract":"<p>A 12-week randomized trial involving 147 participants has found that topiramate was as effective as naltrexone in reducing drinking behaviors in patients with alcohol use disorder (AUD). A secondary analysis found no association between two gene polymorphisms and patient response to the medication treatments.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"35 10","pages":"3"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Topiramate compares favorably to naltrexone for alcohol use disorder\",\"authors\":\"\",\"doi\":\"10.1002/pu.31213\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A 12-week randomized trial involving 147 participants has found that topiramate was as effective as naltrexone in reducing drinking behaviors in patients with alcohol use disorder (AUD). A secondary analysis found no association between two gene polymorphisms and patient response to the medication treatments.</p>\",\"PeriodicalId\":22275,\"journal\":{\"name\":\"The Brown University Psychopharmacology Update\",\"volume\":\"35 10\",\"pages\":\"3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Brown University Psychopharmacology Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/pu.31213\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31213","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Topiramate compares favorably to naltrexone for alcohol use disorder
A 12-week randomized trial involving 147 participants has found that topiramate was as effective as naltrexone in reducing drinking behaviors in patients with alcohol use disorder (AUD). A secondary analysis found no association between two gene polymorphisms and patient response to the medication treatments.
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