Maria Vitale, Ana López, Maria Teresa Truchuelo, Vincenzo Nobile, Massimo Milani, María José Gómez-Sánchez
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引用次数: 0
摘要
背景：敏感性皮肤是一个非常普遍的问题。本研究的目的是评估测试产品在改善敏感皮肤症状方面是否有效和安全：方法：对 24 名健康女性受试者进行了随机分脸临床研究。与载体相比，测试了三种化妆品组合：产品A（西班牙坎塔布里亚的Solía温泉水+硅藻提取物）、产品B（Solía温泉水+硅藻提取物+Annona樱桃果提取物）和产品C（Solía温泉水+硅藻提取物+Annona樱桃果提取物+烟酰胺）。在每次使用研究产品（A、B 或 C）/车辆之前，先涂抹 10%的辣椒素水溶液，模拟敏感皮肤的症状，诱发皮肤刺激。在不同的时间点对刺痛和灼烧感进行评估：结果：与载体相比，所有三种测试产品 A、B 和 C 都能更好地缓解辣椒素引起的症状：结论：测试产品是治疗敏感性皮肤患者刺痛和灼烧感的有趣选择。
Controlled comparison evaluation of the soothing effect of 3 cosmetic products on skin discomfort induced by an irritant chemical agent (capsaicin).
Background: Sensitive skin is a highly prevalent problem. The objective of the study was to assess whether the tested products are effective and safe in terms of improving the symptoms of sensitive skin.
Methods: A clinical randomized split-face study was carried out on 24 healthy female subjects. Three cosmetic combinations were tested versus vehicle: product A (Solía Thermal Spring Water-TSW-from Cantabria, Spain + diatom algae-P. tricornutum-extract), product B (Solía TSW + diatom algae extract + Annona cherimola Fruit Extract) and product C (Solía TSW + diatom algae extract + Annona cherimola Fruit Extract + niacinamide). Prior to each application of the study Product (A, B, or C)/vehicle, 10% of aqueous solution of capsaicin to induce skin irritation was applied, mimicking the symptoms of sensitive skin. Stinging and burning sensations were evaluated at different time points.
Results: All three tested products A, B, and C showed to act better in calming the symptoms induced by capsaicin when compared to the vehicle.
Conclusions: The tested products would be an interesting option for treating stinging and burning sensations in sensitive skin patients.
期刊介绍：
The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques.
The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.
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