先天性红细胞生成性卟啉症：一例补充硫酸亚铁后出现肝功能衰竭和血管性水肿的病例。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-03 DOI:10.1111/pde.15749

Etleva Jorgaqi, Karen Ezenne, Madeline Brown, Albert E Zhou, Amor Khachemoune

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引用次数: 0

摘要

本报告描述了一个不寻常的病例，一名年轻的贫血女性在服用硫酸亚铁后出现急性肝功能不全和血管性水肿。经过详细的皮肤科检查和实验室数据，她被确诊为先天性红细胞生成性卟啉症（CEP）。患者接受了甲基强的松龙静脉注射、红细胞输注、维生素补充和伤口护理等治疗。我们的病例报告强调了医生认识 CEP 的重要性，因为它是一种罕见的疾病，往往会模仿其他慢性卟啉症、各种药物反应和胶原病。

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Congenital Erythropoietic Porphyria: A Case of Hepatic Failure and Angioedema Following Ferrous Sulfate Supplementation.

This report describes an unusual case of a young anemic female who experienced acute hepatic insufficiency and angioedema after ferrous sulfate consumption. Her primary diagnosis of congenital erythropoietic porphyria (CEP) was revealed after a detailed dermatologic examination and laboratory data. The patient was treated with IV methylprednisolone along with red blood cell transfusion, vitamin supplementation, and wound care. Our case report emphasizes the importance of physician awareness of CEP since it is a rare disease that tends to mimic other chronic porphyrias, various drug reactions, and collagenopathies.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.