[免疫球蛋白超家族补体受体调节肝脏免疫的研究进展]。

Q4 Medicine

中国医学科学院学报 Pub Date : 2024-08-01 DOI:10.3881/j.issn.1000-503X.15803

Shu-Sen Yang, Jing-Tao Li, Shu-Guang Yan, Jun-Zhe Jiao

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引用次数: 0

摘要

免疫球蛋白超家族的补体受体（CRIg）是 Kupffer 细胞膜上的一种受体蛋白，它不仅能通过补体结合捕捉流经肝脏的血液中的病原体，还能通过调节肝脏中的免疫细胞介导免疫反应。CRIg不仅能通过补体结合捕获流经肝脏的血液中的病原体，还能通过调节肝脏中的免疫细胞介导免疫反应。最近的研究证实了CRIg在调节肝脏免疫中的作用。本文综述了CRIg的主要作用方式以及CRIg在调节肝脏免疫中的研究进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

[Research Progress in Complement Receptor of the Immunoglobulin Superfamily in Regulating Liver Immunity].

Kupffer cells (KC),an important subset of immune cells in the liver,are essential for maintaining tissue homeostasis and responding quickly to liver damage.The complement receptor of the immunoglobulin superfamily (CRIg) is a receptor protein on the KC membrane.CRIg can not only capture pathogens in the blood flowing through the liver by complement binding but also mediate immune responses by regulating immune cells in the liver.Recent studies have confirmed the role of CRIg in regulating liver immunity.This article reviews the main modes of action of CRIg and the research progress of CRIg in regulating liver immunity.

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来源期刊

中国医学科学院学报 Medicine-Medicine (all)

CiteScore

0.60

自引率

0.00%

发文量

6813

期刊介绍： Acta Academiae Medicinae Sinicae was founded in February 1979. It is a comprehensive medical academic journal published in China and abroad, supervised by the Ministry of Health of the People's Republic of China and sponsored by the Chinese Academy of Medical Sciences and Peking Union Medical College. The journal mainly reports the latest research results, work progress and dynamics in the fields of basic medicine, clinical medicine, pharmacy, preventive medicine, biomedicine, medical teaching and research, aiming to promote the exchange of medical information and improve the academic level of medicine. At present, the journal has been included in 10 famous foreign retrieval systems and their databases [Medline (PubMed online version), Elsevier, EMBASE, CA, WPRIM, ExtraMED, IC, JST, UPD and EBSCO-ASP]; and has been included in important domestic retrieval systems and databases [China Science Citation Database (Documentation and Information Center of the Chinese Academy of Sciences), China Core Journals Overview (Peking University Library), China Science and Technology Paper Statistical Source Database (China Science and Technology Core Journals) (China Institute of Scientific and Technological Information), China Science and Technology Journal Paper and Citation Database (China Institute of Scientific and Technological Information)].