Charcot 神经骨关节病:关键概念综述和循证外科治疗算法。

Frontiers in clinical diabetes and healthcare Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI:10.3389/fcdhc.2024.1344359
Miltiadis Argyropoulos, William Wynell-Mayow, Oscar Johnson, Radwane Faroug, Karanjeev Singh Johal, Rupinderbir Singh Deol, Atef Hakmi, Simon Mordecai
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引用次数: 0

摘要

主要由糖尿病神经病变引起的夏科神经骨关节病(CNO)是一个复杂的问题,发病率很高,随着全球人口结构的变化,医疗负担也越来越重。治疗这种疾病的多个方面需要一个多学科团队(MDT)。这种疾病及其治疗的多因素和非同质性阻碍了基于一级证据的综合指南的制定。虽然目前的趋势是在三级中心对这些患者进行手术治疗,但随着 CNO 发病率的增加,所有单位都有必要在一定程度上对这种疾病进行本地化管理。本文对 Pubmed 和 Embase 2003 年至 2023 年的文献进行了全面检索,检索词包括:"Charcot""神经关节病""糖尿病足""管理""手术""治疗""重建"。我们已将综述结果总结归纳为循证算法,以帮助手术决策过程,并提高整个 MDT 对手术管理的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Charcot neuro-osteoarthropathy: a review of key concepts and an evidence-based surgical management algorithm.

Charcot neuro-osteoarthropathy (CNO), mainly as a result of diabetic neuropathy, is a complex problem which carries significant morbidity, and is an increasing burden on healthcare as demographics change globally. A multi-disciplinary team (MDT) is necessary to treat the multiple facets of this disease. The multifactorial and non-homogenous nature of this condition and its management, has prevented the development of comprehensive guidelines based on level 1 evidence. Although there is a trend to surgically treat these patients in tertiary centres, the increasing prevalence of CNO necessitates the capability of all units to manage this condition to an extent locally. This article conducted a thorough literature search of Pubmed and Embase from 2003 to 2023 including the following search terms; "Charcot" "neuroarthropathy" "diabetic foot" "management" "surgery" "treatment" "reconstruction". The results of this review have been summarised and synthesised into an evidence-based algorithm to aid in the surgical decision-making process, and improve the understanding of surgical management by the whole MDT.

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