野生型"。

IF 2.6 4区生物学 Q3 MICROBIOLOGY

Microbiology-Sgm Pub Date : 2024-08-01 DOI:10.1099/mic.0.001495

Isabel Askenasy, Jemima E V Swain, Pok-Man Ho, Rahan Rudland Nazeer, Amelie Welch, Éva Bernadett Bényei, Leonardo Mancini, Sivan Nir, Pinyu Liao, Martin Welch

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引用次数: 0

摘要

在这篇评论文章中，我们将探讨 "野生型 "一词在微生物学中的含义。在后基因组时代，我们对物种多样性的认识比以往任何时候都更加深刻。我们讨论了基因组异质性、体外进化/选择压力、"野生 "的定义、泛基因组的规模和重要性、基因与基因之间的相互作用（表观遗传）以及 "野生型基因 "的性质。我们的结论是，野生型是一个过时甚至具有误导性的短语，应逐步淘汰。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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'Wild Type'.

In this opinion piece, we consider the meaning of the term 'wild type' in the context of microbiology. This is especially pertinent in the post-genomic era, where we have a greater awareness of species diversity than ever before. Genomic heterogeneity, in vitro evolution/selection pressures, definition of 'the wild', the size and importance of the pan-genome, gene-gene interactions (epistasis), and the nature of the 'wild-type gene' are all discussed. We conclude that wild type is an outdated and even misleading phrase that should be gradually phased out.

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来源期刊

Microbiology-Sgm 生物-微生物学

CiteScore

4.60

自引率

7.10%

发文量

132

审稿时长

3.0 months

期刊介绍： We publish high-quality original research on bacteria, fungi, protists, archaea, algae, parasites and other microscopic life forms. Topics include but are not limited to: Antimicrobials and antimicrobial resistance Bacteriology and parasitology Biochemistry and biophysics Biofilms and biological systems Biotechnology and bioremediation Cell biology and signalling Chemical biology Cross-disciplinary work Ecology and environmental microbiology Food microbiology Genetics Host–microbe interactions Microbial methods and techniques Microscopy and imaging Omics, including genomics, proteomics and metabolomics Physiology and metabolism Systems biology and synthetic biology The microbiome.