地虫：用于治疗某些人类疾病。

IF 3.3 3区医学 Q2 MICROBIOLOGY

Pathogens Pub Date : 2024-08-20 DOI:10.3390/pathogens13080703

Magdalena Szuba, Weronika Stachera, Adrianna Piwko, Marianna Misiak, Renata Rutkevich, Marcin Sota, Lana Atrushi, Leyla Bennacer, Deborah Nzekea, Yen Ching Wu, Arya Taesung Kim, Subin Yu, Nash Ribeiro, Monika Dybicz

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引用次数: 0

摘要

自 "卫生假说 "提出以来，有关寄生虫治疗用途的研究一直在进行。寄生虫可以刺激 Th2 依赖性反应，抑制 Th1 依赖性反应，而这种反应在许多疾病中都会加剧，尤其是过敏性和自身炎症性疾病。在这篇综述中，我们介绍了螺旋体疗法中使用的寄生虫类型，以及它们可能对哪些疾病有用。我们还介绍了迄今为止进行的临床试验结果，这些结果证实了这种疗法的安全性，并提供了可喜的成果。

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Geohelminths: Use in the Treatment of Selected Human Diseases.

Research on the therapeutic use of parasites has been ongoing since the development of the "hygiene hypothesis". Parasites can stimulate the Th2-dependent response and suppress the Th1-dependent response, which is intensified in many diseases, especially allergic and autoinflammatory ones. In this review, we present the types of parasites used in helminth therapy and the range of diseases in which they may be useful. We also present the results of clinical trials conducted so far, which confirm the safety of such therapy and provide promising outcomes.

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来源期刊

Pathogens Medicine-Immunology and Allergy

CiteScore

6.40

自引率

8.10%

发文量

1285

审稿时长

17.75 days

期刊介绍： Pathogens (ISSN 2076-0817) publishes reviews, regular research papers and short notes on all aspects of pathogens and pathogen-host interactions. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodical details must be provided for research articles.