尼日利亚中北部伊洛林慢性鼻窦炎患者的鼻黏膜清除时间。

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Nigerian Postgraduate Medical Journal Pub Date : 2024-07-01 Epub Date: 2024-09-02 DOI:10.4103/npmj.npmj_10_24
Olushola Abdulrahman Afolabi, Segun Segun-Busari, Habeeb Kayodele Omokanye, Muritala Jimoh, Iheayi O Iheagwu, Wasiu Omotosho, Saad O Idris, Kenechukwu Uche-Okonkwo, Biodun Sulyman Alabi, Adekunle David Dunmade, Foluwasayo E Ologe
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引用次数: 0

摘要

背景:目的:本研究旨在确定本地区粘液纤毛清除率的正常值,并研究尼日利亚中北部伊洛林慢性鼻窦炎患者粘液纤毛活动的变化:这是一项前瞻性横断面研究,在家庭医学诊所和耳鼻喉科诊所的就诊患者中,对照组和研究组均有连续同意的参与者:在获得伦理批准后,征得患者的知情同意,填写改良版的有效健康问卷和半结构式问卷,然后对患者进行前鼻镜检查、鼻腔通畅性测试和肺活量测定。过去曾使用糖精试验来测量鼻腔黏膜清除时间:所有信息均输入 SPSS 20 版进行描述性分析,结果以表格和数字形式呈现:125名连续同意的鼻炎患者(研究组)和无鼻炎患者(对照组)接受了鼻腔黏膜纤毛清除试验。研究组有 34 名男性和 91 名女性,男女比例为 1:2.6;对照组有 55 名男性和 70 名女性,男女比例为 1:1.3。研究组的年龄范围为 18 至 68 岁,其中 18-40 岁为标准年龄组。研究组的平均年龄为 35.7 岁,对照组为 33.1 岁。研究组的平均鼻黏膜清除时间为 35.1 分钟(标准差 = 12.32 ± 1.63),而对照组为 14.8 分钟(标准差 = 5.59 ± 0.43):结论:与对照组相比,鼻炎患者的鼻黏膜清除时间延长了约 200%。年龄的增长也与此呈正相关。未来对鼻炎术前和术后治疗方法进行比较的研究将有助于人们了解相关知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Naso-mucociliary Clearance Time among Patients with Chronic Rhinosinusitis in Ilorin, North-central Nigeria.

Context: The mucociliary clearance system is an important component in the prevention of chronic inflammation of the nasal and paranasal sinus.

Aim: The study aims to establish the normal values of mucociliary clearance in our region and to study the variation in mucociliary activity in patients with chronic rhinosinusitis in Ilorin, North-central Nigeria.

Settings and design: This was a prospective, cross-sectional study using consecutive consenting participants in both the control and study groups carried out at both family medicine and otorhinolaryngology clinics among patients attending the clinics.

Subjects and methods: After ethical approval was sought, informed consent was obtained from patients, a modified version of the validated health questionnaire was filled, semi-structured questionnaires were also filled after which patient undergo anterior rhinoscopy, nasal patency test and spirometry was done. The saccharine test has been used to measure nasal-mucociliary clearance time in the past.

Statistical analysis: All information were entered into SPSS version 20 and analysed descriptively, and results were presented in tables and figures.

Results: Consecutive consenting 125 patients with rhinosinusitis (study group) and those without rhinosinusitis (control group) underwent naso-mucociliary clearance test. There were 34 males and 91 females with a male:female ratio of 1:2.6 among the study group and 55 males and 70 females with a male:female ratio of 1:1.3 for the control group. The age range was from 18 to 68 years with 18-40 years constituting the modal age group. The mean age for the studied group was 35.7 years while that of the control group was 33.1 years. The mean naso-mucociliary clearance time among the study group was 35.1 min standard deviation (SD = 12.32 ± 1.63), while among the control group, it was 14.8 min (SD = 5.59 ± 0.43).

Conclusion: Compared to the control group, there was a roughly 200% prolonged increase in the duration of naso-mucociliary clearance time among patients with rhinosinusitis. There was also a positive correlation with increasing age. Future studies comparing the pre-operative and post-operative treatment of rhinosinusitis will contribute to knowledge.

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Nigerian Postgraduate Medical Journal
Nigerian Postgraduate Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.90
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