Yasemin Salık, Pelin Eroglu, Gökhan Zengin, Rıza Binzet
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引用次数: 0
摘要
本研究旨在评估地方性植物 Odontarrhena floribunda 不同部位的乙醇和甲醇提取物的酚类成分、抗氧化、抗菌和抗糖尿病特性。用 1,1-二苯基-1-苦基肼(DPPH)和铜还原抗氧化能力(CUPRAC)测定了 O. floribunda 的抗氧化活性。甲醇根提取物的 DPPH 抗氧化活性最强(IC50:1.68±0.25 μg/mL),乙醇根提取物的 CUPRAC 抗氧化活性最强(λ450:0.68±0.20)。提取物的抗菌活性通过雷沙祖林微孔板法(REMA)显示。与标准化合物相比,所有分析的植物提取物对鲍曼不动杆菌(ATCC 02026)的作用都更强。采用碘量法评估了植物提取物的体外α-淀粉酶和α-葡萄糖苷酶抑制作用。除甲醇叶提取物外,其他提取物都显示出很强的α-葡萄糖苷酶抑制活性(0.88-2.13 mmolTE/g)。这些结果表明,这种地方性植物 O. floribunda 是一种潜在的天然抗氧化剂、抗菌剂和酶抑制剂来源。
Assessment and comparison of phytochemical constituents and biological activities of endemic Odonterrhena floribunda (Brassicaceae) from Türkiye.
This study aimed to evaluate the phenolic profile, antioxidant, antibacterial, and antidiabetic properties of ethanolic and methanolic extracts of the different parts of the endemic Odontarrhena floribunda. The antioxidant activities of O. floribunda were determined with 1,1-diphenyl-1-picrylhydrazyl (DPPH) and the copper-reducing antioxidant capacity (CUPRAC) assays. The strongest antioxidant activity was recorded in methanolic root extract (IC50:1.68±0.25 μg/mL) for DPPH and ethanolic root (λ450:0.68±0.20) extract for CUPRAC. Antibacterial activities of the extracts were displayed by the Resazurin Microplate Method (REMA). All plant extracts analyzed demonstrated stronger effects on Acinetobacter baumannii (ATCC 02026) than those of the standard compound. The in vitro α-amylase and α-glucosidase inhibitory of the plant extract were assessed using the Iodine method. Except for the methanol leaf extract, all other extracts showed strong α-glucosidase inhibitory activity (0.88-2.13 mmolTE/g). These results show that this endemic O. floribunda is a potential natural antioxidant, antibacterial, and enzyme inhibitor source.
期刊介绍:
International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.