人工操作生殖健康低温贮藏设施的努力

IF 3.7 2区 医学 Q1 OBSTETRICS & GYNECOLOGY
Alicia Broussard , Bill Venier , Abeer Salhia Rafati , Angeline Beltsos , Joseph Lee , Jessica Bailey , Denny Sakkas , Michael G. Collins
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引用次数: 0

摘要

研究问题人工体外受精冷冻储存操作的哪些方面是体外受精冷冻储存设施安全运行的共同点,需要胚胎学家付出努力? 设计在四个特征明显的美国体外受精中心(地点α、β、γ和δ),由两名配备数码相机的观察者在两周内收集了 12 名参与者执行冷冻储存任务的时间和运动数据。为了解不同地点的工作流程并协助进行数据分析,对研究参与者和实验室主任进行了非正式访谈。结果平均而言,每次从低温贮藏库检索数据记录需要查询 3.4 次才能确定一根甘蔗,而每次检索平均需要抬起罐子 1.5 次,平均每次抬起时间为 11.8 ± 9.2 秒。在使用低温贮藏设备的总时间中,47.25%的时间是疲劳性的。α、β和γ站点使用一个人填充液氮储存杜瓦,而δ站点则有两名技术人员协同移动和填充杜瓦,填充频率和决定因素以及效率都不同。不同实验室的流程和空间容量存在差异。其中一些问题可以通过整合自动化和技术解决方案来解决。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effort in manual operation of reproductive health cryostorage facilities

Research question

What areas of manual IVF cryostorage operations are common to the safe operation of IVF cryostorage facilities and require effort from embryologists?

Design

Observational time and motion data were collected by two observers equipped with the digital cameras over 2 weeks at four well-characterized US IVF centres (sites α, β, γ and δ) from 12 participants performing cryostorage tasks. To understand the work processes of the different sites and assist in the data analysis, informal interviews were conducted with the study participants and laboratory directors. Data were analysed to identify work processes that might be eliminated or diminished by automation and software improvements.

Results

On average, it took 3.4 data record queries per retrieval from cryostorage to identify a cane, while the canister was lifted an average of 1.5 times per retrieval, with a mean 11.8 ± 9.2 s per lift. Of the total time spent working with cryostorage equipment, 47.25% was of a fatiguing nature. Sites α, β and γ utilized one person to fill the liquid nitrogen storage Dewars, while site δ had two technicians working in tandem to move and fill the Dewars, with different frequencies and determination factors for refills and efficiencies.

Conclusions

This time and motion study demonstrated significant time investment, task redundancy and fatiguing working conditions among embryologists using manual cryostorage processes. There was a disparity of processes and space capacity across different laboratories. Some of these issues may be addressed by the integration of automation and technology solutions.

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来源期刊
Reproductive biomedicine online
Reproductive biomedicine online 医学-妇产科学
CiteScore
7.20
自引率
7.50%
发文量
391
审稿时长
50 days
期刊介绍: Reproductive BioMedicine Online covers the formation, growth and differentiation of the human embryo. It is intended to bring to public attention new research on biological and clinical research on human reproduction and the human embryo including relevant studies on animals. It is published by a group of scientists and clinicians working in these fields of study. Its audience comprises researchers, clinicians, practitioners, academics and patients. Context: The period of human embryonic growth covered is between the formation of the primordial germ cells in the fetus until mid-pregnancy. High quality research on lower animals is included if it helps to clarify the human situation. Studies progressing to birth and later are published if they have a direct bearing on events in the earlier stages of pregnancy.
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