{"title":"壳聚糖涂层氧化钴纳米复合材料的生物制造,用于增强细菌抑制和氧化应激缓解能力","authors":"","doi":"10.1016/j.cplett.2024.141561","DOIUrl":null,"url":null,"abstract":"<div><p>This work focuses on the fabrication of chitosan-coated Co<sub>3</sub>O<sub>4</sub> nanocomposite (NC) through the utilization of <em>Cissus quadrangularis</em> (<em>CQ</em>) plant extract and the assessment of its biological activities. The plant extract contains various phytoconstituents, which can serve as reducing and stabilizing agents. Moreover, the DPPH test verified the antioxidant activity and the enhanced antibacterial efficacy was tested against <em>S. aureus</em> and <em>E. coli</em> bacterial strains. The hemolysis analysis was also utilized to assess the compatibility with human RBCs. These findings have important implications in the pharmaceutical industry as a possible antioxidant and antibacterial agent.</p></div>","PeriodicalId":273,"journal":{"name":"Chemical Physics Letters","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bio-fabrication of chitosan-coated cobalt oxide nanocomposite for enhanced bacterial inhibition and oxidative stress mitigation\",\"authors\":\"\",\"doi\":\"10.1016/j.cplett.2024.141561\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This work focuses on the fabrication of chitosan-coated Co<sub>3</sub>O<sub>4</sub> nanocomposite (NC) through the utilization of <em>Cissus quadrangularis</em> (<em>CQ</em>) plant extract and the assessment of its biological activities. The plant extract contains various phytoconstituents, which can serve as reducing and stabilizing agents. Moreover, the DPPH test verified the antioxidant activity and the enhanced antibacterial efficacy was tested against <em>S. aureus</em> and <em>E. coli</em> bacterial strains. The hemolysis analysis was also utilized to assess the compatibility with human RBCs. These findings have important implications in the pharmaceutical industry as a possible antioxidant and antibacterial agent.</p></div>\",\"PeriodicalId\":273,\"journal\":{\"name\":\"Chemical Physics Letters\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2024-08-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Physics Letters\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0009261424005037\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Physics Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0009261424005037","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Bio-fabrication of chitosan-coated cobalt oxide nanocomposite for enhanced bacterial inhibition and oxidative stress mitigation
This work focuses on the fabrication of chitosan-coated Co3O4 nanocomposite (NC) through the utilization of Cissus quadrangularis (CQ) plant extract and the assessment of its biological activities. The plant extract contains various phytoconstituents, which can serve as reducing and stabilizing agents. Moreover, the DPPH test verified the antioxidant activity and the enhanced antibacterial efficacy was tested against S. aureus and E. coli bacterial strains. The hemolysis analysis was also utilized to assess the compatibility with human RBCs. These findings have important implications in the pharmaceutical industry as a possible antioxidant and antibacterial agent.
期刊介绍:
Chemical Physics Letters has an open access mirror journal, Chemical Physics Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
Chemical Physics Letters publishes brief reports on molecules, interfaces, condensed phases, nanomaterials and nanostructures, polymers, biomolecular systems, and energy conversion and storage.
Criteria for publication are quality, urgency and impact. Further, experimental results reported in the journal have direct relevance for theory, and theoretical developments or non-routine computations relate directly to experiment. Manuscripts must satisfy these criteria and should not be minor extensions of previous work.