产前超声波筛查髋关节发育不良的可行性。

IF 2.9 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Claudia Bevilacqua, Virginia Boscarato, Giovanni Pieroni, Eva Fraternali, Giuliano Lattanzi, Simone Domenico Aspriello, Antonio Pompilio Gigante, Alessandro Cecchi
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引用次数: 0

摘要

背景:髋关节发育不良(DDH)是一种以婴儿期髋关节发育异常为特征的疾病。早期诊断可进行有效治疗,而晚期往往需要进行复杂的手术干预。目前的建议是在产后第 6 到第 8 周进行超声波筛查,通常采用格拉夫法。然而,与临床检查引导下的超声波检查相比,超声波筛查是否能显著提高治疗的可能性,目前尚未达成普遍共识。本研究旨在探讨产前超声检查早期识别 DDH 风险的可行性:这项前瞻性观察研究涉及 100 名在第二和第三个孕期接受胎儿髋部超声检查的孕妇。采用改良格拉夫法计算胎儿的α角和β角。产后,将α角和β角与产前值进行比较:结果:由于难以识别格拉夫地标,第 24 周的产前超声检查结果并不确定,而第 34 周的超声检查被证明是定量测定α角和β角的可靠而安全的方法。产前和产后α角和β角之间存在显著的相关性。此外,在产后发育成熟/不成熟髋关节的患者中观察到产前α和β值的明显差异:结论:产前诊断显示了预测婴儿髋关节发育的前景。结论:产前诊断有望预测婴儿的髋关节发育,但还需要进一步的研究来验证相关性和临床适用性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Feasibility of Prenatal Ultrasonic Screening for Developmental Dysplasia of the Hip.

Background: developmental dysplasia of the hip (DDH) is a condition characterized by abnormal hip development in infancy. Early diagnosis allows for effective treatment, while late presentation often necessitates complex surgical interventions. Current recommendations advise screening between the 6th and 8th week postnatal using an ultrasound, typically employing the Graf method. However, there is no universal consensus on whether ultrasound screening significantly increases treatment likelihood compared to clinical examination-guided ultrasound. This study aims to explore the feasibility of prenatal ultrasound for the early identification of DDH risk.

Methods: This prospective observational study involved 100 pregnant women undergoing fetal hip ultrasounds during the second and third trimesters. Using the modified Graf method, alpha and beta angles were calculated on the fetus. Postnatally, alpha and beta angles were compared with the prenatal values.

Results: Prenatal ultrasound at the 24th week showed inconclusive results because of the difficulty in identification of Graf landmarks, while ultrasound at the 34th week proved to be a reliable and safe method for the quantitative determination of alpha and beta angles. Significant correlations were found between prenatal and postnatal alpha and beta angles. Moreover, significant differences in prenatal alpha and beta values were observed in patients developing mature/immature hips postnatally.

Conclusions: Prenatal diagnostics show promise for predicting infant hip development. Further research is warranted to validate correlation strength and clinical applicability.

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