Ayaka Tsuruno, Shione Kamoshita, Shoichi Hosoya and Kaori Sakurai
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Dichlorotriazine-based multivalent probe for selective affinity labeling of carbohydrate-binding proteins†
A new series of multivalent gold nanoparticle probes bearing different electrophilic groups were synthesized and their affinity labeling reactivities were evaluated. The dichlorotriazine group was identified as a useful protein-reactive label, allowing selective capture of a target protein at nanomolar probe concentrations.