骨膜作为屏障膜引导组织再生的临床疗效:系统回顾和荟萃分析。

Q2 Dentistry
Dental Research Journal Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Shraddha Iyer, Sangamithra Sidharthan, Dharmarajan Gopalakrishnan, Vini Mehta, Chetana Chetana, Meghana Guruprasad, Sharvari Killedar
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引用次数: 0

摘要

研究背景该研究旨在评估骨膜基底移植(PPG)作为屏障膜在引导组织再生(GTR)治疗牙龈退缩、骨内和毛面缺损中的临床疗效:材料和方法: 通过电子和人工搜索,确定了使用 PPG 研究 GTR 并进行 6 个月随访的随机对照/临床试验。主要结果包括:探查深度 (PD)、临床附着水平 (CAL)、骨填充、退缩深度 (RD) 减少、平均牙根覆盖百分比、角化组织宽度 (KTW) 和骨缺损面积 (BDA):共选取了 13 篇文章,其中 6 篇针对退缩,2 篇针对沟槽,5 篇针对骨内。在可能的情况下进行了 Meta 分析,结果以汇总的标准化均值差异(SMDs)表示。在凹陷缺损中,RD 的集合 SMD 为 0.47(95% 置信区间 (CI) = [-0.50-1.44]),KTW 的集合 SMD 为 1.30(95% 置信区间 (CI) = [-0.30-2.91]),PPG 优于对比者。在沟状缺损中,PD集合SMD为1.12(95% CI = [-2.77-0.52]),CAL集合SMD为0.71(95% CI = [-1.09-2.50]),骨填充集合SMD为0.67(95% CI = [-3.34-4.69]),PPG更胜一筹。在骨内缺损中,PD 的集合 SMD 为 0.54(95% CI = [-2.12-1.04]),CAL 的集合 SMD 为 0.23(95% CI = [-1.13-0.68]),BDA 的集合 SMD 为 0.37(95% CI = [-1.58-2.31]),PPG 更受青睐。结果无统计学意义:目前的证据表明,PPG 是成功进行 GTR 的胶原屏障膜的一种有效、可靠的替代方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical efficacy of periosteal pedicle graft as a barrier membrane in guided tissue regeneration: A systematic review and meta-analysis.

Background: The study aims to assess the clinical efficacy of periosteal pedicle graft (PPG) as a barrier membrane in guided tissue regeneration (GTR) for gingival recession, intrabony, and furcation defects.

Materials and methods: Electronic and hand searches were performed to identify randomized controlled/clinical trials investigating GTR using PPG, with 6-month follow-up. Primary outcomes recorded: probing depth (PD), clinical attachment level (CAL), bone fill, recession depth (RD) reduction, percentage of mean root coverage, keratinized tissue width (KTW), and bone defect area (BDA).

Results: Thirteen articles were selected; 6 for recession, 2 for furcation, and 5 for intrabony. Meta-analysis was performed whenever possible, results expressed as pooled standardized mean differences (SMDs). In recession defects, the RD pooled SMD is 0.47 (95% confidence interval (CI) = [-0.50-1.44]), KTW pooled SMD is 1.30 (95% CI = [-0.30-2.91]), favoring PPG over the comparator. In furcation defects, PD pooled SMD is 1.12 (95% CI = [-2.77-0.52]), CAL pooled SMD is 0.71 (95% CI = [-1.09-2.50]), and bone fill pooled SMD is 0.67 (95% CI = [-3.34-4.69]) favoring PPG. In intrabony defects, PD pooled SMD is 0.54 (95% CI = [-2.12-1.04]), CAL pooled SMD is 0.23 (95% CI = [-1.13-0.68]), and BDA pooled SMD is 0.37 (95% CI = [-1.58-2.31]) favoring PPG. The results were not statistically significant.

Conclusion: The current evidence indicates that PPG constitutes a valid and reliable alternative to collagen barrier membranes for successful GTR.

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来源期刊
Dental Research Journal
Dental Research Journal Dentistry-Dentistry (all)
CiteScore
1.70
自引率
0.00%
发文量
70
审稿时长
52 weeks
期刊介绍: Dental Research Journal, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online journal with Bimonthly print on demand compilation of issues published. The journal’s full text is available online at http://www.drjjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal will cover technical and clinical studies related to health, ethical and social issues in field of Dentistry. Articles with clinical interest and implications will be given preference.
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