与急性鼻窦炎相关的早期失败种植体表面分析:一种结合组织学、电子显微镜和 X 射线光谱学的方法。

IF 2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Truc Thi Hoang Nguyen, Mi Young Eo, Mi Hyun Seo, Soung Min Kim
{"title":"与急性鼻窦炎相关的早期失败种植体表面分析:一种结合组织学、电子显微镜和 X 射线光谱学的方法。","authors":"Truc Thi Hoang Nguyen, Mi Young Eo, Mi Hyun Seo, Soung Min Kim","doi":"10.1186/s40902-022-00346-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Even though dental implants are a reliable choice for dental rehabilitation, implant failures due to various etiologies have been reported. Early implant failures account for 2 to 6% of installed implants and are reported to have a higher rate than late failures, regardless of loading time. We herein report three cases of acute sinusitis and early implant failure with implants that failed within 1 month after installation. The aim of this study was to evaluate the surface properties of early failed implants and peri-implant tissue to determine the early osseointegration pattern in acute sinusitis-related failed implants as well as the possible role of surface contamination in the failure of osseointegration.</p><p><strong>Results: </strong>A combined histological, electron microscopy, and X-ray spectroscopy approach was used to characterize the surface of non-osseointegrated titanium implants and the surrounding biological tissues. Morphologic scanning electron microscopy revealed a heterogeneous surface and irregular osseointegration. The implant surface was covered mostly by carbon- and oxygen-rich organic matter. Energy-dispersive X-ray spectroscopy surface analysis of three implants showed the incorporation of some contaminants in both the upper and apical regions. Carbon, nitrogen, sodium, silicon, chlorine, sulfur, gold, and zirconium were detected on the surface of one or more failed implants. Fibrosis, lymphocytic, and macrophage infiltrates and a high activation of osteoclasts surrounding the bone graft particles were detected in the surrounding tissues.</p><p><strong>Conclusions: </strong>The etiology and mechanism of early implant failure, especially in sinus-related cases, as well as the proper management interventions to minimize the rate of early implant failures, are of great concern. No matter how confident and accurate the surgeon's operation, there may be unknown errors in the whole procedure that no one knows about. Rather than errors related to the implant surface, it is expected that there were invisible problems during the evaluation of the patient's own unique sinus mucosal inflammation or the operator's own procedure. Furthermore, well-designed researches are necessary to reveal the effect of material-related factors on acute sinus complication and early implant failure.</p>","PeriodicalId":18357,"journal":{"name":"Maxillofacial Plastic and Reconstructive Surgery","volume":"44 1","pages":"18"},"PeriodicalIF":2.0000,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038979/pdf/","citationCount":"0","resultStr":"{\"title\":\"Analysis of acute sinusitis-related early failed implant surface: a combined histological, electron microscopy, and X-ray spectroscopy approach.\",\"authors\":\"Truc Thi Hoang Nguyen, Mi Young Eo, Mi Hyun Seo, Soung Min Kim\",\"doi\":\"10.1186/s40902-022-00346-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Even though dental implants are a reliable choice for dental rehabilitation, implant failures due to various etiologies have been reported. Early implant failures account for 2 to 6% of installed implants and are reported to have a higher rate than late failures, regardless of loading time. We herein report three cases of acute sinusitis and early implant failure with implants that failed within 1 month after installation. The aim of this study was to evaluate the surface properties of early failed implants and peri-implant tissue to determine the early osseointegration pattern in acute sinusitis-related failed implants as well as the possible role of surface contamination in the failure of osseointegration.</p><p><strong>Results: </strong>A combined histological, electron microscopy, and X-ray spectroscopy approach was used to characterize the surface of non-osseointegrated titanium implants and the surrounding biological tissues. Morphologic scanning electron microscopy revealed a heterogeneous surface and irregular osseointegration. The implant surface was covered mostly by carbon- and oxygen-rich organic matter. Energy-dispersive X-ray spectroscopy surface analysis of three implants showed the incorporation of some contaminants in both the upper and apical regions. Carbon, nitrogen, sodium, silicon, chlorine, sulfur, gold, and zirconium were detected on the surface of one or more failed implants. Fibrosis, lymphocytic, and macrophage infiltrates and a high activation of osteoclasts surrounding the bone graft particles were detected in the surrounding tissues.</p><p><strong>Conclusions: </strong>The etiology and mechanism of early implant failure, especially in sinus-related cases, as well as the proper management interventions to minimize the rate of early implant failures, are of great concern. No matter how confident and accurate the surgeon's operation, there may be unknown errors in the whole procedure that no one knows about. Rather than errors related to the implant surface, it is expected that there were invisible problems during the evaluation of the patient's own unique sinus mucosal inflammation or the operator's own procedure. Furthermore, well-designed researches are necessary to reveal the effect of material-related factors on acute sinus complication and early implant failure.</p>\",\"PeriodicalId\":18357,\"journal\":{\"name\":\"Maxillofacial Plastic and Reconstructive Surgery\",\"volume\":\"44 1\",\"pages\":\"18\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2022-04-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038979/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Maxillofacial Plastic and Reconstructive Surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s40902-022-00346-6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Maxillofacial Plastic and Reconstructive Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s40902-022-00346-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0

摘要

背景:尽管种植牙是牙齿康复的可靠选择,但由于各种病因导致的种植失败也时有报道。早期失败的种植体占已安装种植体的 2%-6%,而且无论装载时间长短,早期失败率都高于晚期失败率。我们在此报告了三例急性鼻窦炎和种植体早期失败的病例,这些病例的种植体在安装后 1 个月内失败。本研究的目的是评估早期失败种植体的表面特性和种植体周围组织,以确定急性鼻窦炎相关失败种植体的早期骨结合模式,以及表面污染在骨结合失败中可能起到的作用:采用组织学、电子显微镜和 X 射线光谱相结合的方法对未骨结合钛种植体的表面和周围生物组织进行了表征。形态学扫描电子显微镜显示表面不均匀,骨结合不规则。种植体表面主要被富含碳和氧的有机物覆盖。对三个种植体进行的能量色散 X 射线光谱表面分析表明,种植体上部和根尖区域都含有一些污染物。在一个或多个失败种植体的表面检测到碳、氮、钠、硅、氯、硫、金和锆。在周围组织中检测到纤维化、淋巴细胞和巨噬细胞浸润以及骨移植颗粒周围破骨细胞的高度活化:早期种植体失败的病因和机制,尤其是与鼻窦相关的病例,以及如何采取适当的管理干预措施将早期种植体失败率降至最低,是我们非常关注的问题。无论外科医生的操作多么自信和准确,整个过程中都可能存在无人知晓的未知错误。与其说是与种植体表面有关的错误,不如说是在对患者自身特有的鼻窦粘膜炎症或操作者自身的手术过程进行评估时出现的隐形问题。此外,有必要进行精心设计的研究,以揭示材料相关因素对急性鼻窦并发症和早期种植失败的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of acute sinusitis-related early failed implant surface: a combined histological, electron microscopy, and X-ray spectroscopy approach.

Background: Even though dental implants are a reliable choice for dental rehabilitation, implant failures due to various etiologies have been reported. Early implant failures account for 2 to 6% of installed implants and are reported to have a higher rate than late failures, regardless of loading time. We herein report three cases of acute sinusitis and early implant failure with implants that failed within 1 month after installation. The aim of this study was to evaluate the surface properties of early failed implants and peri-implant tissue to determine the early osseointegration pattern in acute sinusitis-related failed implants as well as the possible role of surface contamination in the failure of osseointegration.

Results: A combined histological, electron microscopy, and X-ray spectroscopy approach was used to characterize the surface of non-osseointegrated titanium implants and the surrounding biological tissues. Morphologic scanning electron microscopy revealed a heterogeneous surface and irregular osseointegration. The implant surface was covered mostly by carbon- and oxygen-rich organic matter. Energy-dispersive X-ray spectroscopy surface analysis of three implants showed the incorporation of some contaminants in both the upper and apical regions. Carbon, nitrogen, sodium, silicon, chlorine, sulfur, gold, and zirconium were detected on the surface of one or more failed implants. Fibrosis, lymphocytic, and macrophage infiltrates and a high activation of osteoclasts surrounding the bone graft particles were detected in the surrounding tissues.

Conclusions: The etiology and mechanism of early implant failure, especially in sinus-related cases, as well as the proper management interventions to minimize the rate of early implant failures, are of great concern. No matter how confident and accurate the surgeon's operation, there may be unknown errors in the whole procedure that no one knows about. Rather than errors related to the implant surface, it is expected that there were invisible problems during the evaluation of the patient's own unique sinus mucosal inflammation or the operator's own procedure. Furthermore, well-designed researches are necessary to reveal the effect of material-related factors on acute sinus complication and early implant failure.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Maxillofacial Plastic and Reconstructive Surgery
Maxillofacial Plastic and Reconstructive Surgery DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
4.30
自引率
13.00%
发文量
37
审稿时长
13 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信