拼凑 LIN28A 通路拼图

IF 12.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Structural & Molecular Biology Pub Date : 2024-08-21 DOI:10.1038/s41594-024-01380-w

Alperen Yilmaz, Gulben Gurhan, Jacob H. Hanna

引用次数: 0

摘要

最近的两项研究从机理上揭示了 LIN28A 如何控制细胞命运特征的变化，重点研究了 LIN28A 依赖或不依赖 let-7 的作用途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Putting together pieces of the LIN28A pathway puzzle

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Putting together pieces of the LIN28A pathway puzzle

Two recent studies provide mechanistic insights into how LIN28A controls changes in cell fate identity, focusing on either a let-7-independent or let-7-dependent pathway of action involving LIN28A.

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来源期刊

Nature Structural & Molecular Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOPHYSICS

CiteScore

22.00

自引率

1.80%

发文量

160

审稿时长

3-8 weeks

期刊介绍： Nature Structural & Molecular Biology is a comprehensive platform that combines structural and molecular research. Our journal focuses on exploring the functional and mechanistic aspects of biological processes, emphasizing how molecular components collaborate to achieve a particular function. While structural data can shed light on these insights, our publication does not require them as a prerequisite.