青少年特发性脊柱侧凸选择性和非选择性脊柱融合术后的曲线发展:选择性融合术是否稳定?

IF 1.6 Q3 CLINICAL NEUROLOGY
Richard E Campbell, Theodore Rudic, Alexander Hafey, Elizabeth Driskill, Peter O Newton, Keith R Bachmann
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引用次数: 0

摘要

目的:本研究旨在比较选择性融合术和非选择性融合术在术后头五年的纵向疗效:方法:从多中心、前瞻性数据库中检索患者参数。方法:从多中心前瞻性数据库中检索患者参数,纳入伦克1-6、B和C畸形患者。患者被分为两组:选择性融合(SF),如果最后一个植入器械的椎体(LIV)位于腰椎顶或颅顶;或非选择性融合(NSF)。采用广义线性模型(GLM)评估术后1年、2年和5年冠状位和矢状位放射学结果的差异。对各组间术后五年的分类放射学结果、柔韧性、脊柱侧凸研究学会评分(SRS)和再手术率进行了比较。为进行亚组分析建立了匹配队列:本研究共纳入 416 名(SF:261,NF:155)患者,其中包括 353 名女性。术前胸椎和腰椎Cobb角的平均值分别为57.3 ± 8.9和45.3 ± 8.0。GLM显示,SF组术后冠状畸形更大(P 0.05),表明术后畸形矫正相对稳定。SF组腰椎Cobb≥26度的发生率更高(P 结论:SF组的腰椎Cobb≥26度的发生率更高:选择性融合会导致更大的冠状面畸形;然而,与非选择性融合相比,这种畸形不会随着时间的推移而明显加重。选择性脊柱融合术对更多患者可能是一种有益的选择,而不是之前所确定的:证据等级:III。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Curve progression following selective and nonselective spinal fusion for adolescent idiopathic scoliosis: are selective fusions stable?

Purpose: The purpose of this study is to compare postoperative outcomes between selective and non-selective fusions longitudinally over the first five postoperative years.

Methods: Patient parameters were retrieved from a multicenter, prospective, database. Patients with Lenke 1-6, B and C deformities were included. Patients were stratified into 2 groups: selective fusion (SF), if the last instrumented vertebra (LIV) was at or cranial to the lumbar apex, or non-selective fusion (NSF). Differences in coronal and sagittal radiographic outcomes were assessed with generalized linear models (GLMs) at 1-, 2- and 5- year postoperative outcomes. Five-year postoperative categorical radiographic outcomes, flexibility, scoliosis research society scores (SRS), and reoperation rates were compared between groups. Matched cohorts were created for subgroup analysis.

Results: 416 (SF:261, NF:155) patients, including 353 females were included in this study. The mean preoperative thoracic and lumbar Cobb angles were 57.3 ± 8.9 and 45.3 ± 8.0, respectively. GLMs demonstrated greater postoperative coronal deformity in the SF group (p < 0.01); however, the difference between groups did not change overtime (p > 0.05) indicating a relatively stable postoperative deformity correction. The SF group had a greater incidence of lumbar Cobb ≥ 26 degrees (p < 0.01). The NSF group demonstrated worse forward and lateral flexibility at 5-year postoperative outcome (p < 0.05). There was no difference in postoperative SRS scores between the SF and NSF groups. Reoperation rates were similar between groups.

Conclusion: Selective fusion results in greater coronal plane deformity; however, this deformity does not progress significantly over time compared to non-selective fusion. Selective spinal fusion may be a beneficial option for a larger subset of patients than previously identified.

Level of evidence: III.

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来源期刊
CiteScore
3.20
自引率
18.80%
发文量
167
期刊介绍: Spine Deformity the official journal of the?Scoliosis Research Society is a peer-refereed publication to disseminate knowledge on basic science and clinical research into the?etiology?biomechanics?treatment?methods and outcomes of all types of?spinal deformities. The international members of the Editorial Board provide a worldwide perspective for the journal's area of interest.The?journal?will enhance the mission of the Society which is to foster the optimal care of all patients with?spine?deformities worldwide. Articles published in?Spine Deformity?are Medline indexed in PubMed.? The journal publishes original articles in the form of clinical and basic research. Spine Deformity will only publish studies that have institutional review board (IRB) or similar ethics committee approval for human and animal studies and have strictly observed these guidelines. The minimum follow-up period for follow-up clinical studies is 24 months.
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