丘脑中的多结节空泡状神经元肿瘤：病例报告和文献系统回顾。

IF 1.9 3区医学 Q3 CLINICAL NEUROLOGY

Acta Neurochirurgica Pub Date : 2024-08-19 DOI:10.1007/s00701-024-06230-8

Thomas J On, Oscar Alcantar-Garibay, Yuan Xu, Irakliy Abramov, Jennifer M Eschbacher, Nishant Tiwari, Kris A Smith, Mark C Preul

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引用次数: 0

摘要

作者报告了首例丘脑 MVNT 病例，患者是一名 60 岁的男性，有 20 年癫痫史，近期神经功能逐渐衰退，因右侧丘脑无强化肿块接受神经外科评估，推测为低级别胶质瘤。采用左侧对侧大脑半球间经胼胝体入路对肿瘤进行了次全切除。组织学和分子评估显示，MVNT 存在 MAPK 通路激活突变。作者还对病理证实的 MVNT 病例进行了系统回顾，以提供有关这种肿瘤的定位、表现症状和复发的最新文献综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Multinodular and vacuolating neuronal tumor in the thalamus: case report and systematic review of literature.

查看原文本刊更多论文

Multinodular and vacuolating neuronal tumor in the thalamus: case report and systematic review of literature.

The authors present the first reported case of MVNT in the thalamus in a 60-year-old man with a 20-year history of epilepsy and recent progressive neurological decline presented for neurosurgical evaluation for a non-enhancing mass predominantly in the right thalamus presumed to be a low-grade glioma. The tumor was subtotally resected using a left contralateral interhemispheric transcallosal approach. Histological and molecular assessment revealed an MVNT with MAPK pathway-activating mutation. The authors also conducted a systematic review of pathology-proven cases of MVNT to provide an up-to-date overview of the literature on the localization, presenting symptoms, and recurrence of this tumor.

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来源期刊

Acta Neurochirurgica 医学-临床神经学

CiteScore

4.40

自引率

4.20%

发文量

342

审稿时长

1 months

期刊介绍： The journal "Acta Neurochirurgica" publishes only original papers useful both to research and clinical work. Papers should deal with clinical neurosurgery - diagnosis and diagnostic techniques, operative surgery and results, postoperative treatment - or with research work in neuroscience if the underlying questions or the results are of neurosurgical interest. Reports on congresses are given in brief accounts. As official organ of the European Association of Neurosurgical Societies the journal publishes all announcements of the E.A.N.S. and reports on the activities of its member societies. Only contributions written in English will be accepted.