享乐中心的同态饲养

IF 18.9 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Nature metabolism Pub Date : 2024-08-15 DOI:10.1038/s42255-024-01089-6

Zhe Zhao, Sarah A. Stern

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引用次数: 0

摘要

多巴胺多巴核（NAc）的多巴胺 D1 受体可分为不同的转录组亚型，它们对奖赏处理和调节进食行为至关重要。其中一种亚型--NAc SERPINB2+神经元被认为是控制食物摄入和能量平衡所必需的，可作为解决肥胖和饮食失调问题的靶标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Homeostatic feeding in hedonic centres

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Homeostatic feeding in hedonic centres

Dopamine D1 receptors of the nucleus accumbens (NAc) can be divided into different transcriptomic subtypes, and are crucial for reward processing and regulating feeding behaviour. One subtype — the NAc SERPINB2+ neuron— is identified as necessary for the specific control of food intake and energy balance, and could serve as a target for addressing obesity and eating disorders.

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来源期刊

Nature metabolism ENDOCRINOLOGY & METABOLISM-

CiteScore

27.50

自引率

2.40%

发文量

170

期刊介绍： Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.