{"title":"用 AgN 和 AgO 键组装的两种配位聚合物的合成与抗菌活性","authors":"","doi":"10.1016/j.ica.2024.122290","DOIUrl":null,"url":null,"abstract":"<div><p>Two new coordination polymers ({[Ag(<em>p</em>-phda)<sub>2</sub>](BF<sub>4</sub>)} <sub>n</sub> (<strong>1</strong>) and {[Ag<sub>2</sub>(1,5-nds)(DMSO)<sub>2</sub>] DMSO}<sub>n</sub> (<strong>2</strong>) (<em>p</em>-phda: <em>p</em>-phenyldiacetonitrile, 1,5-nds: 1,5-naphthalene disulfonic acid, DMSO: dimethyl sulfoxide) were synthesized and characterized by IR, EA,TG and X-ray single crystal diffraction. <strong>1</strong> was revealed as a 2D “fishing net” assembled by Ag<img>N bonds with BF<sub>4</sub><sup>−</sup> as equilibrium charge. IR and PXRD analysis showed the BF<sub>4</sub><sup>−</sup> can be irreversibly exchanged by six anions varied in atomic numbers, sizes, configurations and coordination abilities. <strong>2</strong> is constructed by Ag<img>O bonds where DMSO function both as guest and bridging ligand. Further diffusion of NO into the solution of <strong>1</strong> and <strong>2</strong> generated two new compounds (<strong>1′</strong> and <strong>2′)</strong>. All four compounds showed excellent broad-spectrum antimicrobial activities against gram-negative bacteria, gram-positive bacteria and yeast. The stronger antibacterial abilities of <strong>1</strong> against <em>S. aureus</em> and <em>P. aeruginosa</em> than those of <strong>2</strong> were evidenced by the smaller minimum inhibitory concentrations of silver ions (AgMICs) and the higher silver ion release rate in aqueous solution. It was concluded that the looser packing of <strong>1</strong> facilitate the silver ions releasing and play a more crucial role than binding mode and ligand-exchangeability. The enhanced <em>P. aeruginosa</em> inhibitions of <strong>1′</strong> and <strong>2′</strong> were elementarily ascribed to NO incorporation, supporting by their increased diameter of inhibition zones and decreased AgMICs.</p></div>","PeriodicalId":13599,"journal":{"name":"Inorganica Chimica Acta","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Syntheses and antimicrobial activities of two coordination polymers assembled with AgN and AgO bonds\",\"authors\":\"\",\"doi\":\"10.1016/j.ica.2024.122290\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Two new coordination polymers ({[Ag(<em>p</em>-phda)<sub>2</sub>](BF<sub>4</sub>)} <sub>n</sub> (<strong>1</strong>) and {[Ag<sub>2</sub>(1,5-nds)(DMSO)<sub>2</sub>] DMSO}<sub>n</sub> (<strong>2</strong>) (<em>p</em>-phda: <em>p</em>-phenyldiacetonitrile, 1,5-nds: 1,5-naphthalene disulfonic acid, DMSO: dimethyl sulfoxide) were synthesized and characterized by IR, EA,TG and X-ray single crystal diffraction. <strong>1</strong> was revealed as a 2D “fishing net” assembled by Ag<img>N bonds with BF<sub>4</sub><sup>−</sup> as equilibrium charge. IR and PXRD analysis showed the BF<sub>4</sub><sup>−</sup> can be irreversibly exchanged by six anions varied in atomic numbers, sizes, configurations and coordination abilities. <strong>2</strong> is constructed by Ag<img>O bonds where DMSO function both as guest and bridging ligand. Further diffusion of NO into the solution of <strong>1</strong> and <strong>2</strong> generated two new compounds (<strong>1′</strong> and <strong>2′)</strong>. All four compounds showed excellent broad-spectrum antimicrobial activities against gram-negative bacteria, gram-positive bacteria and yeast. The stronger antibacterial abilities of <strong>1</strong> against <em>S. aureus</em> and <em>P. aeruginosa</em> than those of <strong>2</strong> were evidenced by the smaller minimum inhibitory concentrations of silver ions (AgMICs) and the higher silver ion release rate in aqueous solution. It was concluded that the looser packing of <strong>1</strong> facilitate the silver ions releasing and play a more crucial role than binding mode and ligand-exchangeability. The enhanced <em>P. aeruginosa</em> inhibitions of <strong>1′</strong> and <strong>2′</strong> were elementarily ascribed to NO incorporation, supporting by their increased diameter of inhibition zones and decreased AgMICs.</p></div>\",\"PeriodicalId\":13599,\"journal\":{\"name\":\"Inorganica Chimica Acta\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2024-08-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Inorganica Chimica Acta\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0020169324003815\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inorganica Chimica Acta","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0020169324003815","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Syntheses and antimicrobial activities of two coordination polymers assembled with AgN and AgO bonds
Two new coordination polymers ({[Ag(p-phda)2](BF4)} n (1) and {[Ag2(1,5-nds)(DMSO)2] DMSO}n (2) (p-phda: p-phenyldiacetonitrile, 1,5-nds: 1,5-naphthalene disulfonic acid, DMSO: dimethyl sulfoxide) were synthesized and characterized by IR, EA,TG and X-ray single crystal diffraction. 1 was revealed as a 2D “fishing net” assembled by AgN bonds with BF4− as equilibrium charge. IR and PXRD analysis showed the BF4− can be irreversibly exchanged by six anions varied in atomic numbers, sizes, configurations and coordination abilities. 2 is constructed by AgO bonds where DMSO function both as guest and bridging ligand. Further diffusion of NO into the solution of 1 and 2 generated two new compounds (1′ and 2′). All four compounds showed excellent broad-spectrum antimicrobial activities against gram-negative bacteria, gram-positive bacteria and yeast. The stronger antibacterial abilities of 1 against S. aureus and P. aeruginosa than those of 2 were evidenced by the smaller minimum inhibitory concentrations of silver ions (AgMICs) and the higher silver ion release rate in aqueous solution. It was concluded that the looser packing of 1 facilitate the silver ions releasing and play a more crucial role than binding mode and ligand-exchangeability. The enhanced P. aeruginosa inhibitions of 1′ and 2′ were elementarily ascribed to NO incorporation, supporting by their increased diameter of inhibition zones and decreased AgMICs.
期刊介绍：
Inorganica Chimica Acta is an established international forum for all aspects of advanced Inorganic Chemistry. Original papers of high scientific level and interest are published in the form of Articles and Reviews.
Topics covered include:
• chemistry of the main group elements and the d- and f-block metals, including the synthesis, characterization and reactivity of coordination, organometallic, biomimetic, supramolecular coordination compounds, including associated computational studies;
• synthesis, physico-chemical properties, applications of molecule-based nano-scaled clusters and nanomaterials designed using the principles of coordination chemistry, as well as coordination polymers (CPs), metal-organic frameworks (MOFs), metal-organic polyhedra (MPOs);
• reaction mechanisms and physico-chemical investigations computational studies of metalloenzymes and their models;
• applications of inorganic compounds, metallodrugs and molecule-based materials.
Papers composed primarily of structural reports will typically not be considered for publication.
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