{"title":"通过调解肿瘤微环境中的免疫细胞来对抗癌症的 PDE5 抑制剂：基于人工智能的未来药物再利用探索方法 (3/2024)","authors":"Zhenzhan Zhang, Donghua Huang, Junjie Feng, Wangji Li, Zhe Wang, Mengting Lu, Yangyang Luo, Weihao Yang, Zhou Xu, Qingfeng Xie, Wenfu Ding, Xin Tan, Wenjun He, Guoxin Li, Hao Liu, Shangtong Lei","doi":"10.1002/inmd.12116","DOIUrl":null,"url":null,"abstract":"<p>This review summarized the effects of PDE5 inhibitors on immune cells in the tumor microenvironment (TME). By combining new methods of artificial intelligence (AI), it proposes that AI can explore the drug targets of PDE5 inhibitors on immune cells in the TME and predict pharmacodynamic targets and responses, has significant scientific implications.\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":100686,"journal":{"name":"Interdisciplinary Medicine","volume":"2 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/inmd.12116","citationCount":"0","resultStr":"{\"title\":\"PDE5 Inhibitors Against Cancer Via Mediating Immune Cells in Tumor Microenvironment: AI-Based Approach for Future Drug Repurposing Exploration (3/2024)\",\"authors\":\"Zhenzhan Zhang, Donghua Huang, Junjie Feng, Wangji Li, Zhe Wang, Mengting Lu, Yangyang Luo, Weihao Yang, Zhou Xu, Qingfeng Xie, Wenfu Ding, Xin Tan, Wenjun He, Guoxin Li, Hao Liu, Shangtong Lei\",\"doi\":\"10.1002/inmd.12116\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>This review summarized the effects of PDE5 inhibitors on immune cells in the tumor microenvironment (TME). By combining new methods of artificial intelligence (AI), it proposes that AI can explore the drug targets of PDE5 inhibitors on immune cells in the TME and predict pharmacodynamic targets and responses, has significant scientific implications.\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":100686,\"journal\":{\"name\":\"Interdisciplinary Medicine\",\"volume\":\"2 3\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/inmd.12116\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Interdisciplinary Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/inmd.12116\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Interdisciplinary Medicine","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/inmd.12116","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
PDE5 Inhibitors Against Cancer Via Mediating Immune Cells in Tumor Microenvironment: AI-Based Approach for Future Drug Repurposing Exploration (3/2024)
This review summarized the effects of PDE5 inhibitors on immune cells in the tumor microenvironment (TME). By combining new methods of artificial intelligence (AI), it proposes that AI can explore the drug targets of PDE5 inhibitors on immune cells in the TME and predict pharmacodynamic targets and responses, has significant scientific implications.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
