用于监测小分子和确定单个神经元分泌能力的暗场共振瑞利散射生物传感器（Adv.）

IF 6.4 3区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Advanced Materials Technologies Pub Date : 2024-08-07 DOI:10.1002/admt.202470065

Yi Su, Guoguang Rong, Sumin Bian, Pengbo Wang, Lingfei Li, Yun-Hsuan Chen, Chao Huang, Hongyong Zhang, Mohamad Sawan

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引用次数: 0

摘要

共振瑞利散射准确监测神经递质和精确描述神经元的分泌能力对于有效治疗神经系统疾病至关重要。在编号为 2301701 的文章中，Mohamad Sawan 及其合作者发现，小神经递质与适配体的结合会引起构象变化，从而改变金纳米簇-适配体复合物的有效半径。这种变化可以从共振瑞利散射强度中检测到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Dark-Field Resonance Rayleigh Scattering Biosensor to Monitor Small Molecules and Determine the Secretory Ability of Single Neuron (Adv. Mater. Technol. 15/2024)

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Dark-Field Resonance Rayleigh Scattering Biosensor to Monitor Small Molecules and Determine the Secretory Ability of Single Neuron (Adv. Mater. Technol. 15/2024)

Resonance Rayleigh Scattering

Accurate monitoring of neurotransmitters and precise characterization of the secretory ability of neurons are essential for effective treatment of neurological diseases. In article number 2301701, Mohamad Sawan and co-workers discover that the binding of small neurotransmitters to aptamers induces a conformational change that alters the effective radius of Au nanoclusters-aptamer complexes. This change can be detected in the resonance Rayleigh scattering intensity.

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来源期刊

Advanced Materials Technologies Materials Science-General Materials Science

CiteScore

10.20

自引率

4.40%

发文量

566

期刊介绍： Advanced Materials Technologies Advanced Materials Technologies is the new home for all technology-related materials applications research, with particular focus on advanced device design, fabrication and integration, as well as new technologies based on novel materials. It bridges the gap between fundamental laboratory research and industry.