利用拉曼光谱评估阻塞性黄疸患者胆汁中的胆红素浓度

IF 0.8 4区物理与天体物理 Q4 OPTICS

Optics and Spectroscopy Pub Date : 2024-08-07 DOI:10.1134/S0030400X24020152

E. V. Potapova, V. N. Prizemin, D. S. Sumin, A. V. Mamoshin

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引用次数: 0

摘要

摘要拉曼光谱（RS）被广泛应用于生物医学领域，用于检测底物中的各种化合物及其浓度。在这项研究中，RS 被用来检测通过胆管造口引流导管获得的不同病因的阻塞性黄疸（OJ）患者肝胆中的胆红素。利用 785 纳米的激发波长确定了胆红素的光谱带（1258-1264 和 1615-1620 cm-1）。研究发现，通过评估胆汁中的胆红素，可以预测 OJ 患者胆道减压后肝脏排泄功能的恢复情况和康复动态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Assessment of Bilirubin Concentrations in the Bile of Patients with Obstructive Jaundice by Raman Spectroscopy

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Assessment of Bilirubin Concentrations in the Bile of Patients with Obstructive Jaundice by Raman Spectroscopy

Raman spectroscopy (RS) is widely used in biomedicine to detect various chemical compounds in substrates, as well as to determine their concentration. In this work, RS was used to detect bilirubin in the hepatic bile of patients with obstructive jaundice (OJ) of different etiologies obtained via a cholangiostomy drainage catheter. The spectral bands of bilirubin (1258–1264 and 1615–1620 cm^–1) were identified using the excitation wavelength of 785 nm. It was found that the assessment of bilirubin in bile allows to predict the recovery of excretory liver function and the dynamics of convalescence of patients with OJ after biliary decompression.

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来源期刊

Optics and Spectroscopy 物理-光谱学

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

4.5 months

期刊介绍： Optics and Spectroscopy (Optika i spektroskopiya), founded in 1956, presents original and review papers in various fields of modern optics and spectroscopy in the entire wavelength range from radio waves to X-rays. Topics covered include problems of theoretical and experimental spectroscopy of atoms, molecules, and condensed state, lasers and the interaction of laser radiation with matter, physical and geometrical optics, holography, and physical principles of optical instrument making.